Version 5.4
Homo sapiens Gene: SLC13A5
Summary
InnateDB Gene IDBG-22524.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol SLC13A5
Gene Name solute carrier family 13 (sodium-dependent citrate transporter), member 5
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000141485
Encoded Proteins
IDBP-22526
solute carrier family 13 (sodium-dependent citrate transporter), member 5
IDBP-22528
solute carrier family 13 (sodium-dependent citrate transporter), member 5
IDBP-364484
solute carrier family 13 (sodium-dependent citrate transporter), member 5
IDBP-758079
IDBP-762443
IDBP-762072
IDBP-758720
IDBP-760789
IDBP-763926
IDBP-760624
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary SLC13A5 is a tricarboxylate plasma transporter with a preference for citrate.[supplied by OMIM, Apr 2004]
Gene Information
Type Protein coding
Genomic Location Chromosome 17:6684713-6713567
Strand Reverse strand
Band p13.1
Transcripts
ENST00000381074 ENSP00000370464
ENST00000293800 ENSP00000293800
ENST00000433363 ENSP00000406220
ENST00000575230 ENSP00000460903
ENST00000572352 ENSP00000461622
ENST00000572094 ENSP00000461495
ENST00000574580
ENST00000570687 ENSP00000460037
ENST00000576323 ENSP00000461554
ENST00000574824
ENST00000573648 ENSP00000459372
ENST00000572727 ENSP00000466899
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
Experimentally validated
Total 1 [view]
Protein-Protein 0
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005215 transporter activity
GO:0005343 organic acid:sodium symporter activity
GO:0015137 citrate transmembrane transporter activity
GO:0015141 succinate transmembrane transporter activity
GO:0015142 tricarboxylic acid transmembrane transporter activity
GO:0017153 sodium:dicarboxylate symporter activity
Biological Process
GO:0006814 sodium ion transport
GO:0006842 tricarboxylic acid transport
GO:0015744 succinate transport
GO:0015746 citrate transport
GO:0035674 tricarboxylic acid transmembrane transport
GO:0055085 transmembrane transport
Cellular Component
GO:0005886 plasma membrane
GO:0016020 membrane
GO:0016021 integral component of membrane
GO:0016323 basolateral plasma membrane
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000020805
View Gene Order
ENSBTAG00000004680
Not yet available
Pathways
NETPATH
REACTOME
REACT_20646
Sodium-coupled sulphate, di- and tri-carboxylate transporters pathway
REACT_19305
Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds pathway
REACT_15518
Transmembrane transport of small molecules pathway
REACT_19118
SLC-mediated transmembrane transport pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt Q86YT5
TrEMBL Q68D44 Q6ZMG6
UniProt Splice Variant
Entrez Gene 284111
UniGene Hs.399496 Hs.611809
RefSeq NM_001284509 NM_001143838 NM_001284510 NM_177550 XM_006721504
HUGO HGNC:23089
OMIM 608305
CCDS CCDS67137 CCDS11079 CCDS45593 CCDS67136
HPRD 10512
IMGT
EMBL AC004706 AK127797 AK172779 AK172785 AY151833 BC104795 BC112151 BC143689 CH471108 CR749584
GenPept AAI04796 AAI12152 AAI43690 AAN86530 BAD18760 BAD18766 BAG54572 CAH18382 EAW90292
RNA Seq Atlas 102723404 284111

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca