Version 5.4
Homo sapiens Gene: OXSM
Summary
InnateDB Gene IDBG-22740.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol OXSM
Gene Name 3-oxoacyl-ACP synthase, mitochondrial
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000151093
Encoded Proteins
IDBP-22742
3-oxoacyl-ACP synthase, mitochondrial
IDBP-368283
3-oxoacyl-ACP synthase, mitochondrial
IDBP-368290
3-oxoacyl-ACP synthase, mitochondrial
IDBP-368292
3-oxoacyl-ACP synthase, mitochondrial
IDBP-368299
3-oxoacyl-ACP synthase, mitochondrial
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene encodes a beta-ketoacyl synthetase. The encoded enzyme is required for elongation of fatty acid chains in the mitochondria. Alternatively spliced transcript variants have been described.[provided by RefSeq, Feb 2009]
Gene Information
Type Protein coding
Genomic Location Chromosome 3:25782917-25794534
Strand Forward strand
Band p24.2
Transcripts
ENST00000280701 ENSP00000280701
ENST00000452098 ENSP00000392334
ENST00000420173 ENSP00000411303
ENST00000448177 ENSP00000404115
ENST00000449808
ENST00000428266 ENSP00000409817
ENST00000460195
ENST00000464688
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0003824 catalytic activity
GO:0004315 3-oxoacyl-[acyl-carrier-protein] synthase activity
GO:0016740 transferase activity
GO:0016747 transferase activity, transferring acyl groups other than amino-acyl groups
Biological Process
GO:0006633 fatty acid biosynthetic process
GO:0006637 acyl-CoA metabolic process
GO:0008152 metabolic process
GO:0051790 short-chain fatty acid biosynthetic process
GO:0051792 medium-chain fatty acid biosynthetic process
Cellular Component
GO:0005739 mitochondrion
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000021786
View Gene Order
ENSBTAG00000007031
Not yet available
Pathways
NETPATH
REACTOME
KEGG
hsa00061
Fatty acid biosynthesis pathway
hsa00780
Biotin metabolism pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.55781 Hs.739184
RefSeq NM_001145391 NM_017897 XM_006713216 XM_006713217
HUGO
OMIM
CCDS CCDS2643 CCDS46780
HPRD 07931
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca