Version 5.4
Homo sapiens Gene: SCAMP2
Summary
InnateDB Gene IDBG-22760.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol SCAMP2
Gene Name secretory carrier membrane protein 2
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000140497
Encoded Proteins
IDBP-22762
secretory carrier membrane protein 2
IDBP-747636
IDBP-746291
IDBP-746844
IDBP-745359
IDBP-745643
IDBP-746416
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene product belongs to the SCAMP family of proteins which are secretory carrier membrane proteins. They function as carriers to the cell surface in post-golgi recycling pathways. Different family members are highly related products of distinct genes, and are usually expressed together. These findings suggest that the SCAMPs may function at the same site during vesicular transport rather than in separate pathways. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 15:74843730-74873365
Strand Reverse strand
Band q24.1
Transcripts
ENST00000268099 ENSP00000268099
ENST00000565345 ENSP00000454464
ENST00000567638
ENST00000564529 ENSP00000457564
ENST00000563829
ENST00000566557
ENST00000569904 ENSP00000454741
ENST00000569124
ENST00000566480 ENSP00000455377
ENST00000563663 ENSP00000455963
ENST00000569251
ENST00000562363 ENSP00000457890
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 7 experimentally validated interaction(s) in this database.
Experimentally validated
Total 7 [view]
Protein-Protein 7 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
GO:0006892 post-Golgi vesicle-mediated transport
GO:0015031 protein transport
Cellular Component
GO:0005634 nucleus
GO:0005794 Golgi apparatus
GO:0016021 integral component of membrane
GO:0030133 transport vesicle
GO:0032588 trans-Golgi network membrane
GO:0043231 intracellular membrane-bounded organelle
GO:0055038 recycling endosome membrane
GO:0070062 extracellular vesicular exosome
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000040188
View Gene Order
ENSBTAG00000005844
Not yet available
Pathways
NETPATH
REACTOME
KEGG
INOH
PID NCI
arf6_traffickingpathway
Arf6 trafficking events
Cross-References
SwissProt
TrEMBL H3BQW2
UniProt Splice Variant
Entrez Gene 102725331
UniGene Hs.458917 Hs.618691
RefSeq NM_005697
HUGO HGNC:10564
OMIM 606912
CCDS CCDS10271
HPRD 06073
IMGT
EMBL AC091230
GenPept
RNA Seq Atlas 10066 102725331

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca