Version 5.4
Homo sapiens Gene: DEPDC1B
Summary
InnateDB Gene IDBG-22834.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol DEPDC1B
Gene Name DEP domain containing 1B
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000035499
Encoded Proteins
IDBP-22838
DEP domain containing 1B
IDBP-368259
DEP domain containing 1B
IDBP-475726
DEP domain containing 1B
IDBP-482677
DEP domain containing 1B
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 5:60596912-60700190
Strand Reverse strand
Band q12.1
Transcripts
ENST00000265036 ENSP00000265036
ENST00000453022 ENSP00000389101
ENST00000512078 ENSP00000427527
ENST00000509006
ENST00000505017
ENST00000512452 ENSP00000426979
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 3 [view]
Protein-Protein 3 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005096 GTPase activator activity
Biological Process
GO:0007165 signal transduction
GO:0007264 small GTPase mediated signal transduction
GO:0035556 intracellular signal transduction
GO:0043547 positive regulation of GTPase activity
GO:0051056 regulation of small GTPase mediated signal transduction
Cellular Component
GO:0005622 intracellular
GO:0005829 cytosol
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000021697
View Gene Order
ENSBTAG00000017026
Not yet available
Pathways
NETPATH
REACTOME
REACT_11051
Rho GTPase cycle pathway
REACT_11044
Signaling by Rho GTPases pathway
REACT_111102
Signal Transduction pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt
TrEMBL D6RDV9
UniProt Splice Variant
Entrez Gene 55789
UniGene Hs.482233 Hs.743369
RefSeq NM_001145208 NM_018369
HUGO HGNC:24902
OMIM
CCDS CCDS3977 CCDS47214
HPRD 16794
IMGT
EMBL AC016591 AC109133
GenPept
RNA Seq Atlas 55789

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca