Version 5.4
Homo sapiens Gene: NAP1L4
Summary
InnateDB Gene IDBG-23836.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol NAP1L4
Gene Name nucleosome assembly protein 1-like 4
Synonyms hNAP2; NAP1L4b; NAP2; NAP2L
Species Homo sapiens
Ensembl Gene ENSG00000205531
Encoded Proteins
IDBP-23838
nucleosome assembly protein 1-like 4
IDBP-230209
nucleosome assembly protein 1-like 4
IDBP-362243
nucleosome assembly protein 1-like 4
IDBP-362247
nucleosome assembly protein 1-like 4
IDBP-362249
nucleosome assembly protein 1-like 4
IDBP-590322
nucleosome assembly protein 1-like 4
IDBP-602473
nucleosome assembly protein 1-like 4
IDBP-586590
nucleosome assembly protein 1-like 4
IDBP-595218
nucleosome assembly protein 1-like 4
IDBP-584963
nucleosome assembly protein 1-like 4
IDBP-591104
nucleosome assembly protein 1-like 4
IDBP-597248
nucleosome assembly protein 1-like 4
IDBP-597803
nucleosome assembly protein 1-like 4
IDBP-600203
nucleosome assembly protein 1-like 4
IDBP-811475
nucleosome assembly protein 1-like 4
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene encodes a member of the nucleosome assembly protein (NAP) family which can interact with both core and linker histones. It can shuttle between the cytoplasm and nucleus, suggesting a role as a histone chaperone. This gene is one of several located near the imprinted gene domain of 11p15.5, an important tumor-suppressor gene region. Alterations in this region have been associated with the Beckwith-Wiedemann syndrome, Wilms tumor, rhabdomyosarcoma, adrenocortical carcinoma, and lung, ovarian, and breast cancer. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 11:2944431-2992377
Strand Reverse strand
Band p15.4
Transcripts
ENST00000380542 ENSP00000369915
ENST00000399614 ENSP00000382523
ENST00000448187 ENSP00000387783
ENST00000430811 ENSP00000405912
ENST00000455338 ENSP00000412048
ENST00000469805
ENST00000492594
ENST00000469089
ENST00000492685 ENSP00000431644
ENST00000483643
ENST00000526115 ENSP00000436397
ENST00000526023
ENST00000528363
ENST00000528261
ENST00000532325 ENSP00000436488
ENST00000529361 ENSP00000435327
ENST00000528968 ENSP00000434759
ENST00000530064 ENSP00000432126
ENST00000526842 ENSP00000431799
ENST00000531291 ENSP00000437130
ENST00000534372 ENSP00000433512
ENST00000620138 ENSP00000481412
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 38 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.
Experimentally validated
Total 38 [view]
Protein-Protein 36 [view]
Protein-DNA 2 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 3 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0044822 poly(A) RNA binding
GO:0051082 unfolded protein binding
Biological Process
GO:0006334 nucleosome assembly
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000059119
View Gene Order
ENSBTAG00000022160
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.665264 Hs.731784
RefSeq NM_005969
HUGO
OMIM
CCDS CCDS41599
HPRD 11873
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca