Homo sapiens Gene: RPS29
Summary
InnateDB Gene IDBG-238371.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol RPS29
Gene Name ribosomal protein S29
Synonyms DBA13; S29;
Species Homo sapiens
Ensembl Gene ENSG00000213741
Encoded Proteins
ribosomal protein S29
ribosomal protein S29
ribosomal protein S29
ribosomal protein S29
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 40S subunit and a member of the S14P family of ribosomal proteins. The protein, which contains a C2-C2 zinc finger-like domain that can bind to zinc, can enhance the tumor suppressor activity of Ras-related protein 1A (KREV1). It is located in the cytoplasm. Variable expression of this gene in colorectal cancers compared to adjacent normal tissues has been observed, although no correlation between the level of expression and the severity of the disease has been found. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2013]
Gene Information
Type Protein coding
Genomic Location Chromosome 14:49570984-49599164
Strand Reverse strand
Band q21.3
Transcripts
ENST00000245458 ENSP00000245458
ENST00000396020 ENSP00000379339
ENST00000557367
ENST00000557111 ENSP00000478117
ENST00000554075
ENST00000557519
ENST00000556230
ENST00000611563 ENSP00000479892
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 55 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 55 [view]
Protein-Protein 53 [view]
Protein-DNA 2 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003735 structural constituent of ribosome
GO:0008270 zinc ion binding
Biological Process
GO:0000184 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
GO:0006412 translation
GO:0006413 translational initiation
GO:0006414 translational elongation
GO:0006415 translational termination
GO:0006614 SRP-dependent cotranslational protein targeting to membrane
GO:0010467 gene expression
GO:0016032 viral process
GO:0016070 RNA metabolic process
GO:0016071 mRNA metabolic process
GO:0019058 viral life cycle
GO:0019083 viral transcription
GO:0044267 cellular protein metabolic process
Cellular Component
GO:0005622 intracellular
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0005840 ribosome
GO:0015935 small ribosomal subunit
GO:0022627 cytosolic small ribosomal subunit
GO:0070062 extracellular vesicular exosome
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
Method
Confidence
Comments
Non-SSD Ortholog
Possible paralog/unusual divergence/ gene prediction error
Not yet available
Non-SSD Ortholog
Possible paralog/unusual divergence/ gene prediction error
Pathways
NETPATH
REACTOME
Eukaryotic Translation Initiation pathway
Influenza Infection pathway
SRP-dependent cotranslational protein targeting to membrane pathway
Nonsense-Mediated Decay (NMD) pathway
Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) pathway
Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S pathway
Formation of a pool of free 40S subunits pathway
Influenza Viral RNA Transcription and Replication pathway
Translation pathway
Translation initiation complex formation pathway
Eukaryotic Translation Termination pathway
Metabolism of proteins pathway
Cap-dependent Translation Initiation pathway
Ribosomal scanning and start codon recognition pathway
Eukaryotic Translation Elongation pathway
Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) pathway
Influenza Life Cycle pathway
GTP hydrolysis and joining of the 60S ribosomal subunit pathway
Formation of the ternary complex, and subsequently, the 43S complex pathway
Viral mRNA Translation pathway
Peptide chain elongation pathway
L13a-mediated translational silencing of Ceruloplasmin expression pathway
Gene Expression pathway
Disease pathway
KEGG
Ribosome pathway
INOH
PID BIOCARTA
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene
RefSeq NM_001030001 NM_001032
HUGO
OMIM
CCDS CCDS32072 CCDS9685
HPRD
IMGT
EMBL
GenPept
RNA Seq Atlas