Homo sapiens Gene: SYNJ2BP
Summary
InnateDB Gene IDBG-241827.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol SYNJ2BP
Gene Name synaptojanin 2 binding protein
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000213463
Encoded Proteins
synaptojanin 2 binding protein
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This locus represents naturally occurring read-through transcription between the neighboring SYNJ2BP (synaptojanin 2 binding protein) and COX16 (COX16 cytochrome c oxidase assembly homolog (S. cerevisiae)) genes on chromosome 14. The read-through transcript produces a fusion protein that shares sequence identity with each individual gene product. Alternate splicing results in multiple transcript variants that encode different isoforms. [provided by RefSeq, Feb 2011]
Gene Information
Type Protein coding
Genomic Location Chromosome 14:70366496-70417061
Strand Reverse strand
Band q24.2
Transcripts
ENST00000256366 ENSP00000256366
ENST00000554216
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 22 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.
Experimentally validated
Total 22 [view]
Protein-Protein 20 [view]
Protein-DNA 2 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 3 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0008022 protein C-terminus binding
GO:0070699 type II activin receptor binding
Biological Process
GO:0002092 positive regulation of receptor internalization
GO:0032926 negative regulation of activin receptor signaling pathway
GO:0032927 positive regulation of activin receptor signaling pathway
GO:0048312 intracellular distribution of mitochondria
GO:2000010 positive regulation of protein localization to cell surface
Cellular Component
GO:0005739 mitochondrion
GO:0009986 cell surface
GO:0031307 integral component of mitochondrial outer membrane
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
Method
Confidence
Comments
SSD Ortholog
Ortholog supports species divergence
Not yet available
SSD Ortholog
Ortholog supports species divergence
Cross-References
SwissProt P57105
TrEMBL A0A024R670
UniProt Splice Variant
Entrez Gene 55333
UniGene Hs.443661 Hs.707005
RefSeq NM_018373
HUGO HGNC:18955
OMIM 609411
CCDS CCDS9803
HPRD
IMGT
EMBL AK002133 AY534623 BC007704 CH471061
GenPept AAH07704 AAT01566 BAA92098 EAW81032 EAW81033
RNA Seq Atlas 55333