Version 5.4
Homo sapiens Gene: CRIP1
Summary
InnateDB Gene IDBG-245465.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol CRIP1
Gene Name cysteine-rich protein 1 (intestinal)
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000213145
Encoded Proteins
IDBP-23503
cysteine-rich protein 1 (intestinal)
IDBP-245467
cysteine-rich protein 1 (intestinal)
IDBP-295243
cysteine-rich protein 1 (intestinal)
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Cysteine-rich intestinal protein (CRIP) belongs to the LIM/double zinc finger protein family, members of which include cysteine- and glycine-rich protein-1 (CSRP1; MIM 123876), rhombotin-1 (RBTN1; MIM 186921), rhombotin-2 (RBTN2; MIM 180385), and rhombotin-3 (RBTN3; MIM 180386). CRIP may be involved in intestinal zinc transport (Hempe and Cousins, 1991 [PubMed 1946385]).[supplied by OMIM, Mar 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 14:105486317-105488947
Strand Forward strand
Band q32.33
Transcripts
ENST00000330233 ENSP00000332449
ENST00000392531 ENSP00000376315
ENST00000409393 ENSP00000386340
ENST00000496700
ENST00000460900
ENST00000461556
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 5 experimentally validated interaction(s) in this database.
Experimentally validated
Total 5 [view]
Protein-Protein 5 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0003680 AT DNA binding
GO:0008270 zinc ion binding
GO:0008301 DNA binding, bending
GO:0042277 peptide binding
Biological Process
GO:0006955 immune response
GO:0007507 heart development
GO:0008283 cell proliferation
GO:0008630 intrinsic apoptotic signaling pathway in response to DNA damage
GO:0010033 response to organic substance
GO:0010043 response to zinc ion
GO:0010468 regulation of gene expression
GO:0060741 prostate gland stromal morphogenesis
GO:0071236 cellular response to antibiotic
GO:0071493 cellular response to UV-B
Cellular Component
GO:0005737 cytoplasm
Orthologs
No orthologs found for this gene
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene
RefSeq NM_001311
HUGO
OMIM
CCDS CCDS10004
HPRD 00469
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca