Mus musculus Gene: Neu2
Summary
InnateDB Gene IDBG-254372.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Neu2
Gene Name neuraminidase 2
Synonyms MBS; MSS; MTS;
Species Mus musculus
Ensembl Gene ENSMUSG00000079434
Encoded Proteins
neuraminidase 2
neuraminidase 2
neuraminidase 2
neuraminidase 2
neuraminidase 2
neuraminidase 2
neuraminidase 2
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000115488:
This gene belongs to a family of glycohydrolytic enzymes which remove sialic acid residues from glycoproteins and glycolipids. Expression studies in COS7 cells confirmed that this gene encodes a functional sialidase. Its cytosolic localization was demonstrated by cell fractionation experiments. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 1:87509889-87597845
Strand Forward strand
Band D
Transcripts
ENSMUST00000070898 ENSMUSP00000065439
ENSMUST00000166055 ENSMUSP00000132099
ENSMUST00000166259 ENSMUSP00000132513
ENSMUST00000163606 ENSMUSP00000127777
ENSMUST00000164128 ENSMUSP00000127913
ENSMUST00000165109 ENSMUSP00000126509
ENSMUST00000172222 ENSMUSP00000131409
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0052794 exo-alpha-(2->3)-sialidase activity
GO:0052795 exo-alpha-(2->6)-sialidase activity
GO:0052796 exo-alpha-(2->8)-sialidase activity
Biological Process
GO:0006689 ganglioside catabolic process
GO:0009313 oligosaccharide catabolic process
Cellular Component
GO:0005737 cytoplasm
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
Method
Confidence
Comments
SSD Ortholog
Ortholog supports species divergence
Not yet available
SSD Ortholog
Ortholog supports species divergence
Pathways
NETPATH
REACTOME
Synthesis of substrates in N-glycan biosythesis pathway
Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein pathway
Glycosphingolipid metabolism pathway
Metabolism pathway
Sphingolipid metabolism pathway
Metabolism of proteins pathway
Post-translational protein modification pathway
Metabolism of lipids and lipoproteins pathway
Asparagine N-linked glycosylation pathway
Sialic acid metabolism pathway
KEGG
Other glycan degradation pathway
Sphingolipid metabolism pathway
INOH
PID BIOCARTA
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
Sphingolipid metabolism pathway
Metabolism of lipids and lipoproteins pathway
Post-translational protein modification pathway
Synthesis of substrates in N-glycan biosythesis pathway
Asparagine N-linked glycosylation pathway
Sialic acid metabolism pathway
Metabolism of proteins pathway
Glycosphingolipid metabolism pathway
Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein pathway
Metabolism pathway
KEGG
Other glycan degradation pathway
Sphingolipid metabolism pathway
INOH
PID BIOCARTA
PID NCI
Cross-References
SwissProt Q9JMH3
TrEMBL C0KJU9 E9Q0I0 E9Q0P5 E9Q2Z0 Q0VGI4 Q8R0U7
UniProt Splice Variant
Entrez Gene 23956
UniGene Mm.143717
RefSeq NM_001160163 NM_001160164 NM_001160165 NM_015750 XM_006529523 XM_006529524
OMIM
CCDS CCDS15135 CCDS48308 CCDS48309
HPRD
IMGT
MGI ID MGI:1344417
MGI Symbol Neu2
EMBL AB028023 AB048604 AC102564 AC157811 AF139059 BC026408 BC105657 BC105658 BC105659 BC105661 CH466520 FJ613504
GenPept AAH26408 AAI05658 AAI05659 AAI05660 AAI05662 ACM77811 BAA92867 BAB39152 EDL40156 EDL40158
RNA Seq Atlas 23956