Version 5.4
| Mus musculus Gene: Neu2 | |||||||||
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| Summary | |||||||||
| InnateDB Gene | IDBG-254372.6 | ||||||||
| Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||
| Gene Symbol | Neu2 | ||||||||
| Gene Name | neuraminidase 2 | ||||||||
| Synonyms | MBS; MSS; MTS | ||||||||
| Species | Mus musculus | ||||||||
| Ensembl Gene | ENSMUSG00000079434 | ||||||||
| Encoded Proteins |
neuraminidase 2
neuraminidase 2
neuraminidase 2
neuraminidase 2
neuraminidase 2
neuraminidase 2
neuraminidase 2
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| Protein Structure | |||||||||
| Useful resources | Stemformatics EHFPI ImmGen | ||||||||
| Entrez Gene | |||||||||
| Summary |
This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000115488:
This gene belongs to a family of glycohydrolytic enzymes which remove sialic acid residues from glycoproteins and glycolipids. Expression studies in COS7 cells confirmed that this gene encodes a functional sialidase. Its cytosolic localization was demonstrated by cell fractionation experiments. [provided by RefSeq, Jul 2008] |
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| Gene Information | |||||||||
| Type | Protein coding | ||||||||
| Genomic Location | Chromosome 1:87509889-87597845 | ||||||||
| Strand | Forward strand | ||||||||
| Band | D | ||||||||
| Transcripts | |||||||||
| Interactions | |||||||||
| Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
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| Gene Ontology | |||||||||
Molecular Function |
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| Biological Process |
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| Cellular Component |
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| Orthologs | |||||||||
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Species
Homo sapiens
Bos taurus
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Gene ID
Gene Order
Not yet available
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| Pathways | |||||||||
| NETPATH | |||||||||
| REACTOME |
Synthesis of substrates in N-glycan biosythesis pathway
Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein pathway
Glycosphingolipid metabolism pathway
Metabolism pathway
Sphingolipid metabolism pathway
Metabolism of proteins pathway
Post-translational protein modification pathway
Metabolism of lipids and lipoproteins pathway
Asparagine N-linked glycosylation pathway
Sialic acid metabolism pathway
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| KEGG |
Sphingolipid metabolism pathway
Other glycan degradation pathway
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| INOH | |||||||||
| PID NCI | |||||||||
| Pathway Predictions based on Human Orthology Data | |||||||||
| NETPATH | |||||||||
| REACTOME |
Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein pathway
Asparagine N-linked glycosylation pathway
Glycosphingolipid metabolism pathway
Sphingolipid metabolism pathway
Metabolism of lipids and lipoproteins pathway
Post-translational protein modification pathway
Synthesis of substrates in N-glycan biosythesis pathway
Sialic acid metabolism pathway
Metabolism of proteins pathway
Metabolism pathway
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| KEGG |
Sphingolipid metabolism pathway
Other glycan degradation pathway
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| INOH | |||||||||
| PID NCI | |||||||||
| Cross-References | |||||||||
| SwissProt | |||||||||
| TrEMBL | C0KJU9 E9Q0I0 E9Q0P5 E9Q2Z0 Q0VGI4 Q8R0U7 | ||||||||
| UniProt Splice Variant | |||||||||
| Entrez Gene | 23956 | ||||||||
| UniGene | Mm.143717 | ||||||||
| RefSeq | NM_001160163 NM_001160164 NM_001160165 NM_015750 XM_006529523 XM_006529524 | ||||||||
| OMIM | |||||||||
| CCDS | CCDS48308 CCDS15135 CCDS48309 | ||||||||
| HPRD | |||||||||
| IMGT | |||||||||
| MGI ID | MGI:1344417 | ||||||||
| MGI Symbol | Neu2 | ||||||||
| EMBL | AB028023 AB048604 AC102564 AC157811 AF139059 BC026408 BC105657 BC105658 BC105659 BC105661 CH466520 FJ613504 | ||||||||
| GenPept | AAH26408 AAI05658 AAI05659 AAI05660 AAI05662 ACM77811 BAA92867 BAB39152 EDL40156 EDL40158 | ||||||||
| RNA Seq Atlas | 23956 | ||||||||