Version 5.4
Homo sapiens Gene: ARHGEF40
Summary
InnateDB Gene IDBG-2544.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol ARHGEF40
Gene Name Rho guanine nucleotide exchange factor (GEF) 40
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000165801
Encoded Proteins
IDBP-2546
Rho guanine nucleotide exchange factor (GEF) 40
IDBP-589757
Rho guanine nucleotide exchange factor (GEF) 40
IDBP-594244
Rho guanine nucleotide exchange factor (GEF) 40
IDBP-599807
Rho guanine nucleotide exchange factor (GEF) 40
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 14:21070270-21090240
Strand Forward strand
Band q11.2
Transcripts
ENST00000298694 ENSP00000298694
ENST00000555038 ENSP00000451335
ENST00000556399 ENSP00000451655
ENST00000553709 ENSP00000452283
ENST00000555232
ENST00000555052
ENST00000554514
ENST00000557498
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 6 experimentally validated interaction(s) in this database.
Experimentally validated
Total 6 [view]
Protein-Protein 6 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005089 Rho guanyl-nucleotide exchange factor activity
Biological Process
GO:0032321 positive regulation of Rho GTPase activity
GO:0035023 regulation of Rho protein signal transduction
Cellular Component
GO:0005737 cytoplasm
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000004562
View Gene Order
ENSBTAG00000013401
Not yet available
Cross-References
SwissProt
TrEMBL G3V485
UniProt Splice Variant
Entrez Gene 55701
UniGene Hs.35125 Hs.601545 Hs.733352
RefSeq NM_001278529 NM_001278530 NM_018071
HUGO HGNC:25516
OMIM 610018
CCDS CCDS32041
HPRD 13335
IMGT
EMBL AL161668
GenPept
RNA Seq Atlas 55701

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca