Version 5.4
Homo sapiens Gene: OXSR1
Summary
InnateDB Gene IDBG-25753.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol OXSR1
Gene Name oxidative-stress responsive 1
Synonyms OSR1
Species Homo sapiens
Ensembl Gene ENSG00000172939
Encoded Proteins
IDBP-25755
oxidative-stress responsive 1
IDBP-371970
oxidative-stress responsive 1
IDBP-371976
oxidative-stress responsive 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary The product of this gene belongs to the Ser/Thr protein kinase family of proteins. It regulates downstream kinases in response to environmental stress, and may play a role in regulating the actin cytoskeleton. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 3:38165089-38255488
Strand Forward strand
Band p22.2
Transcripts
ENST00000311806 ENSP00000311713
ENST00000446845 ENSP00000415851
ENST00000426620 ENSP00000398356
ENST00000492714
ENST00000483695
ENST00000467900
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 31 experimentally validated interaction(s) in this database.
Experimentally validated
Total 31 [view]
Protein-Protein 28 [view]
Protein-DNA 2 [view]
Protein-RNA 1 [view]
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0000287 magnesium ion binding
GO:0004672 protein kinase activity
GO:0004674 protein serine/threonine kinase activity
GO:0004702 receptor signaling protein serine/threonine kinase activity
GO:0004713 protein tyrosine kinase activity
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0016772 transferase activity, transferring phosphorus-containing groups
Biological Process
GO:0006468 protein phosphorylation
GO:0006979 response to oxidative stress
GO:0018107 peptidyl-threonine phosphorylation
GO:0023014 signal transduction by phosphorylation
GO:0035556 intracellular signal transduction
GO:0071476 cellular hypotonic response
GO:1901017 negative regulation of potassium ion transmembrane transporter activity
GO:1901380 negative regulation of potassium ion transmembrane transport
GO:2000681 negative regulation of rubidium ion transport
GO:2000687 negative regulation of rubidium ion transmembrane transporter activity
Cellular Component
GO:0005737 cytoplasm
GO:0070062 extracellular vesicular exosome
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000036737
View Gene Order
ENSBTAG00000014927
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.475970 Hs.606692 Hs.609150
RefSeq NM_005109
HUGO
OMIM
CCDS CCDS2675
HPRD 06809
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca