Version 5.4
Homo sapiens Gene: SLC5A3
Summary
InnateDB Gene IDBG-2685.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol SLC5A3
Gene Name solute carrier family 5 (sodium/myo-inositol cotransporter), member 3
Synonyms BCW2; SMIT; SMIT1; SMIT2
Species Homo sapiens
Ensembl Gene ENSG00000198743
Encoded Proteins
IDBP-2689
solute carrier family 5 (sodium/myo-inositol cotransporter), member 3
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 21:34073570-34106260
Strand Forward strand
Band q22.11
Transcripts
ENST00000381151 ENSP00000370543
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 5 experimentally validated interaction(s) in this database.
Experimentally validated
Total 5 [view]
Protein-Protein 3 [view]
Protein-DNA 2 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005215 transporter activity
GO:0005367 myo-inositol:sodium symporter activity
GO:0005524 ATP binding
GO:0042626 ATPase activity, coupled to transmembrane movement of substances
Biological Process
GO:0006020 inositol metabolic process
GO:0006810 transport
GO:0006814 sodium ion transport
GO:0007422 peripheral nervous system development
GO:0015798 myo-inositol transport
GO:0043576 regulation of respiratory gaseous exchange
GO:0055085 transmembrane transport
Cellular Component
GO:0005886 plasma membrane
GO:0005887 integral component of plasma membrane
GO:0016020 membrane
GO:0016021 integral component of membrane
Orthologs
Species
Mus musculus
Gene ID
Gene Order
ENSMUSG00000089774
View Gene Order
Pathways
NETPATH
REACTOME
REACT_19188
Inositol transporters pathway
REACT_19165
Na+-dependent glucose transporters pathway
REACT_19305
Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds pathway
REACT_9441
Hexose transport pathway
REACT_15518
Transmembrane transport of small molecules pathway
REACT_200783
Myoclonic epilepsy of Lafora pathway
REACT_474
Metabolism of carbohydrates pathway
REACT_111217
Metabolism pathway
REACT_19118
SLC-mediated transmembrane transport pathway
REACT_116125
Disease pathway
REACT_200833
Glycogen storage diseases pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.302742 Hs.610123 Hs.613905 Hs.710454 Hs.710797
RefSeq NM_006933
HUGO
OMIM
CCDS CCDS33549
HPRD 02708
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca