Version 5.4
Homo sapiens Gene: BET1
Summary
InnateDB Gene IDBG-27278.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol BET1
Gene Name blocked early in transport 1 homolog (S. cerevisiae)
Synonyms HBET1
Species Homo sapiens
Ensembl Gene ENSG00000105829
Encoded Proteins
IDBP-27280
blocked early in transport 1 homolog (S. cerevisiae)
IDBP-27282
blocked early in transport 1 homolog (S. cerevisiae)
IDBP-382039
blocked early in transport 1 homolog (S. cerevisiae)
IDBP-382041
blocked early in transport 1 homolog (S. cerevisiae)
IDBP-382043
blocked early in transport 1 homolog (S. cerevisiae)
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene encodes a golgi-associated membrane protein that participates in vesicular transport from the endoplasmic reticulum (ER) to the Golgi complex. The encoded protein functions as a soluble N-ethylaleimide-sensitive factor attachment protein receptor and may be involved in the docking of ER-derived vesicles with the cis-Golgi membrane. Alternatively spliced transcript variants encoding different isoforms have been described but their full-length nature has not been determined. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 7:93962762-94004382
Strand Reverse strand
Band q21.3
Transcripts
ENST00000357520 ENSP00000350125
ENST00000222547 ENSP00000222547
ENST00000433727 ENSP00000391228
ENST00000457139 ENSP00000401260
ENST00000425626 ENSP00000413063
ENST00000471446
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 10 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 10 [view]
Protein-Protein 8 [view]
Protein-DNA 2 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0019905 syntaxin binding
Biological Process
GO:0006888 ER to Golgi vesicle-mediated transport
GO:0015031 protein transport
GO:0048280 vesicle fusion with Golgi apparatus
Cellular Component
GO:0000139 Golgi membrane
GO:0005789 endoplasmic reticulum membrane
GO:0005801 cis-Golgi network
GO:0016020 membrane
GO:0016021 integral component of membrane
GO:0031985 Golgi cisterna
Orthologs
Species
Mus musculus
Gene ID
Gene Order
ENSMUSG00000032757
View Gene Order
Pathways
NETPATH
REACTOME
KEGG
hsa04130
SNARE interactions in vesicular transport pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL Q68DU7
UniProt Splice Variant
Entrez Gene 10282
UniGene Hs.489132 Hs.712954
RefSeq XM_005250109 NM_005868
HUGO HGNC:14562
OMIM 605456
CCDS CCDS5635
HPRD 16107
IMGT
EMBL AC006378 CR749267
GenPept CAH18123
RNA Seq Atlas 10282

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca