Version 5.4
Homo sapiens Gene: BTF3
Summary
InnateDB Gene IDBG-27987.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol BTF3
Gene Name basic transcription factor 3
Synonyms BETA-NAC; BTF3a; BTF3b; NACB
Species Homo sapiens
Ensembl Gene ENSG00000145741
Encoded Proteins
IDBP-27991
basic transcription factor 3
IDBP-27993
basic transcription factor 3
IDBP-477983
basic transcription factor 3
IDBP-485220
basic transcription factor 3
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene encodes the basic transcription factor 3. This protein forms a stable complex with RNA polymerase IIB and is required for transcriptional initiation. Alternative splicing results in multiple transcript variants encoding different isoforms. This gene has multiple pseudogenes. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 5:73498408-73505635
Strand Forward strand
Band q13.2
Transcripts
ENST00000335895 ENSP00000338516
ENST00000380591 ENSP00000369965
ENST00000512257
ENST00000514505
ENST00000514360
ENST00000510787
ENST00000508901
ENST00000507081 ENSP00000420978
ENST00000509708 ENSP00000425490
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 22 experimentally validated interaction(s) in this database.
Experimentally validated
Total 22 [view]
Protein-Protein 21 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0044822 poly(A) RNA binding
Biological Process
GO:0001701 in utero embryonic development
GO:0006355 regulation of transcription, DNA-templated
GO:0006366 transcription from RNA polymerase II promoter
GO:0015031 protein transport
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000021660
View Gene Order
ENSBTAG00000010012
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene 689
UniGene Hs.567241
RefSeq NM_001037637 NM_001207
HUGO HGNC:1125
OMIM 602542
CCDS CCDS34185 CCDS4019
HPRD 03966
IMGT
EMBL
GenPept
RNA Seq Atlas 102724313 689

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca