Homo sapiens Gene: FXC1
Summary
InnateDB Gene IDBG-29223.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol FXC1
Gene Name fracture callus 1 homolog (rat)
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000132286
Encoded Proteins
fracture callus 1 homolog (rat)
fracture callus 1 homolog (rat)
fracture callus 1 homolog (rat)
fracture callus 1 homolog (rat)
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary FXC1, or TIMM10B, belongs to a family of evolutionarily conserved proteins that are organized in heterooligomeric complexes in the mitochondrial intermembrane space. These proteins mediate the import and insertion of hydrophobic membrane proteins into the mitochondrial inner membrane.[supplied by OMIM, Apr 2004]
Gene Information
Type Protein coding
Genomic Location Chromosome 11:6481447-6484679
Strand Forward strand
Band p15.4
Transcripts
ENST00000254616 ENSP00000254616
ENST00000528908
ENST00000530751 ENSP00000436579
ENST00000531462 ENSP00000433087
ENST00000533379 ENSP00000436948
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 4 experimentally validated interaction(s) in this database.
Experimentally validated
Total 4 [view]
Protein-Protein 3 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0046872 metal ion binding
Biological Process
GO:0006626 protein targeting to mitochondrion
GO:0007160 cell-matrix adhesion
GO:0044267 cellular protein metabolic process
Cellular Component
GO:0005743 mitochondrial inner membrane
GO:0005758 mitochondrial intermembrane space
GO:0042719 mitochondrial intermembrane space protein transporter complex
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
Method
Confidence
Comments
SSD Ortholog
Ortholog supports species divergence
Not yet available
SSD Ortholog
Ortholog supports species divergence
Pathways
NETPATH
REACTOME
Metabolism of proteins pathway
Mitochondrial protein import pathway
KEGG
INOH
PID BIOCARTA
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.54943 Hs.702646 Hs.743551
RefSeq NM_012192
HUGO
OMIM
CCDS CCDS7766
HPRD 16242
IMGT
EMBL
GenPept
RNA Seq Atlas