Homo sapiens Gene: MIR155HG
Summary
InnateDB Gene IDBG-296872.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol MIR155HG
Gene Name MIR155 host gene (non-protein coding)
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000234883
Encoded Proteins
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009] MicroRNAs (miRNAs), such as miRNA155, are endogenous noncoding RNAs of about 22 nucleotides that regulate mRNAs by targeting them for cleavage or translational repression. The primary miRNA transcript containing the mature miRNA155 sequence, pri-miRNA155, is also referred to as BIC (Kluiver et al., 2005 [PubMed 16041695]).[supplied by OMIM, Mar 2008]
Gene Information
Type lincRNA
Genomic Location Chromosome 21:25561909-25575168
Strand Forward strand
Band q21.3
Transcripts
ENST00000456917
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Orthologs
No orthologs found for this gene
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene 406947
UniGene Hs.697120
RefSeq
HUGO HGNC:35460
OMIM 609337
CCDS
HPRD
IMGT
EMBL
GenPept
RNA Seq Atlas 114614 406947