Homo sapiens Gene: MATN2
Summary
InnateDB Gene IDBG-29765.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol MATN2
Gene Name matrilin 2
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000132561
Encoded Proteins
matrilin 2
matrilin 2
matrilin 2
matrilin 2
matrilin 2
matrilin 2
matrilin 2
matrilin 2
matrilin 2
matrilin 2
matrilin 2
matrilin 2
matrilin 2
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene encodes a member of the von Willebrand factor A domain containing protein family. This family of proteins is thought to be involved in the formation of filamentous networks in the extracellular matrices of various tissues. This protein contains five von Willebrand factor A domains. The specific function of this gene has not yet been determined. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 8:97868840-98036716
Strand Forward strand
Band q22.1
Transcripts
ENST00000254898 ENSP00000254898
ENST00000521689 ENSP00000429977
ENST00000524308 ENSP00000430221
ENST00000523490
ENST00000522025 ENSP00000429010
ENST00000520160
ENST00000520016 ENSP00000430487
ENST00000518154 ENSP00000429622
ENST00000521041 ENSP00000430396
ENST00000519585 ENSP00000429042
ENST00000518238
ENST00000522270 ENSP00000429825
ENST00000521952 ENSP00000429256
ENST00000517321 ENSP00000429885
ENST00000518370
ENST00000519582 ENSP00000430358
ENST00000523561
ENST00000522135 ENSP00000429354
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 12 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 12 [view]
Protein-Protein 12 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
GO:0005509 calcium ion binding
GO:0005515 protein binding
Biological Process
GO:0001764 neuron migration
GO:0007411 axon guidance
GO:0008150 biological_process
GO:0008347 glial cell migration
GO:0031104 dendrite regeneration
GO:0031175 neuron projection development
GO:0048678 response to axon injury
Cellular Component
GO:0005576 extracellular region
GO:0005578 proteinaceous extracellular matrix
GO:0005604 basement membrane
GO:0031012 extracellular matrix
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
Method
Confidence
Comments
SSD Ortholog
Ortholog supports species divergence
Not yet available
SSD Ortholog
Ortholog supports species divergence
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.668456
RefSeq NM_002380 NM_030583
HUGO
OMIM
CCDS CCDS55264 CCDS55265
HPRD 03660
IMGT
EMBL
GenPept
RNA Seq Atlas