Version 5.4
Homo sapiens Gene: SCAMP4
Summary
InnateDB Gene IDBG-298147.4
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol SCAMP4
Gene Name secretory carrier membrane protein 4
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000227500
Encoded Proteins
IDBP-15146
secretory carrier membrane protein 4
IDBP-292650
secretory carrier membrane protein 4
IDBP-811459
secretory carrier membrane protein 4
IDBP-362668
secretory carrier membrane protein 4
IDBP-811461
secretory carrier membrane protein 4
IDBP-760319
IDBP-811464
secretory carrier membrane protein 4
IDBP-811465
secretory carrier membrane protein 4
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Secretory carrier membrane proteins (SCAMPs) are widely distributed integral membrane proteins implicated in membrane trafficking. Most SCAMPs (e.g., SCAMP1; MIM 606911) have N-terminal cytoplasmic NPF (arg-pro-phe) repeats, 4 central transmembrane regions, and a short C-terminal cytoplasmic tail. These SCAMPs likely have a role in endocytosis that is mediated by their NPF repeats. Other SCAMPs, such as SCAMP4, lack the NPF repeats and are therefore unlikely to function in endocytosis (summary by Fernandez-Chacon and Sudhof, 2000 [PubMed 11050114]).[supplied by OMIM, Feb 2011]
Gene Information
Type Protein coding
Genomic Location Chromosome 19:1905214-1926013
Strand Forward strand
Band p13.3
Transcripts
ENST00000316097 ENSP00000316007
ENST00000409472 ENSP00000386865
ENST00000452128
ENST00000414057 ENSP00000479672
ENST00000411971 ENSP00000388185
ENST00000460767 ENSP00000481989
ENST00000489554
ENST00000472442
ENST00000590266 ENSP00000465199
ENST00000588907 ENSP00000478264
ENST00000588555
ENST00000585335
ENST00000621748 ENSP00000479083
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
Experimentally validated
Total 2 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 1 [view]
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
Biological Process
GO:0015031 protein transport
Cellular Component
GO:0016021 integral component of membrane
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000078441
View Gene Order
ENSBTAG00000045762
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.144980
RefSeq NM_079834
HUGO
OMIM
CCDS CCDS45903
HPRD 11536
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca