Homo sapiens Gene: SCAMP4
Summary
InnateDB Gene IDBG-298147.4
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol SCAMP4
Gene Name secretory carrier membrane protein 4
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000227500
Encoded Proteins
secretory carrier membrane protein 4
secretory carrier membrane protein 4
secretory carrier membrane protein 4
secretory carrier membrane protein 4
secretory carrier membrane protein 4
secretory carrier membrane protein 4
secretory carrier membrane protein 4
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Secretory carrier membrane proteins (SCAMPs) are widely distributed integral membrane proteins implicated in membrane trafficking. Most SCAMPs (e.g., SCAMP1; MIM 606911) have N-terminal cytoplasmic NPF (arg-pro-phe) repeats, 4 central transmembrane regions, and a short C-terminal cytoplasmic tail. These SCAMPs likely have a role in endocytosis that is mediated by their NPF repeats. Other SCAMPs, such as SCAMP4, lack the NPF repeats and are therefore unlikely to function in endocytosis (summary by Fernandez-Chacon and Sudhof, 2000 [PubMed 11050114]).[supplied by OMIM, Feb 2011]
Gene Information
Type Protein coding
Genomic Location Chromosome 19:1905214-1926013
Strand Forward strand
Band p13.3
Transcripts
ENST00000316097 ENSP00000316007
ENST00000409472 ENSP00000386865
ENST00000452128
ENST00000414057 ENSP00000479672
ENST00000411971 ENSP00000388185
ENST00000460767 ENSP00000481989
ENST00000489554
ENST00000472442
ENST00000590266 ENSP00000465199
ENST00000588907 ENSP00000478264
ENST00000588555
ENST00000585335
ENST00000621748 ENSP00000479083
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
Experimentally validated
Total 2 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 1 [view]
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
Biological Process
GO:0015031 protein transport
Cellular Component
GO:0016021 integral component of membrane
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
Method
Confidence
Comments
Non-SSD Ortholog
Possible paralog/unusual divergence/ gene prediction error
Not yet available
Non-SSD Ortholog
Possible paralog/unusual divergence/ gene prediction error
Cross-References
SwissProt
TrEMBL K7EJJ4
UniProt Splice Variant
Entrez Gene 113178
UniGene Hs.144980
RefSeq NM_079834
HUGO HGNC:30385
OMIM 613764
CCDS CCDS45903
HPRD 11536
IMGT
EMBL AC012615
GenPept
RNA Seq Atlas 113178