Version 5.4
Homo sapiens Gene: GREB1
Summary
InnateDB Gene IDBG-29963.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol GREB1
Gene Name growth regulation by estrogen in breast cancer 1
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000196208
Encoded Proteins
IDBP-29965
growth regulation by estrogen in breast cancer 1
IDBP-29967
growth regulation by estrogen in breast cancer 1
IDBP-29969
growth regulation by estrogen in breast cancer 1
IDBP-29973
growth regulation by estrogen in breast cancer 1
IDBP-29975
growth regulation by estrogen in breast cancer 1
IDBP-238128
growth regulation by estrogen in breast cancer 1
IDBP-364140
growth regulation by estrogen in breast cancer 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene is an estrogen-responsive gene that is an early response gene in the estrogen receptor-regulated pathway. It is thought to play an important role in hormone-responsive tissues and cancer. Three alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 2:11534116-11642788
Strand Forward strand
Band p25.1
Transcripts
ENST00000234142 ENSP00000234142
ENST00000381486 ENSP00000370896
ENST00000263834 ENSP00000263834
ENST00000381483 ENSP00000370892
ENST00000389825 ENSP00000374475
ENST00000396123 ENSP00000379429
ENST00000432985 ENSP00000403886
ENST00000470980
ENST00000472040
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
Experimentally validated
Total 2 [view]
Protein-Protein 0
Protein-DNA 2 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
Biological Process
Cellular Component
GO:0016021 integral component of membrane
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000036523
View Gene Order
ENSBTAG00000015402
Not yet available
Pathways
NETPATH
REACTOME
KEGG
INOH
PID NCI
era_genomic_pathway
Validated nuclear estrogen receptor alpha network
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.467733 Hs.611740
RefSeq NM_014668 NM_033090 NM_148903 XM_005246192 XM_005246195 XM_005246196 XM_005246197 XM_006711904 XM_006711905 XM_006711906 XM_006711908
HUGO
OMIM
CCDS CCDS33146 CCDS33147 CCDS42655
HPRD 13611
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca