Version 5.4
Homo sapiens Gene: OSR2
Summary
InnateDB Gene IDBG-30128.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol OSR2
Gene Name odd-skipped related 2 (Drosophila)
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000164920
Encoded Proteins
IDBP-30130
odd-skipped related 2 (Drosophila)
IDBP-374229
odd-skipped related 2 (Drosophila)
IDBP-374236
odd-skipped related 2 (Drosophila)
IDBP-483143
odd-skipped related 2 (Drosophila)
IDBP-482555
odd-skipped related 2 (Drosophila)
IDBP-482848
odd-skipped related 2 (Drosophila)
IDBP-477604
odd-skipped related 2 (Drosophila)
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary OSR2 is a mammalian homolog of the Drosophila odd-skipped family of transcription factors (Lan et al., 2004 [PubMed 15175245]).[supplied by OMIM, Mar 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 8:98944403-98952104
Strand Forward strand
Band q22.2
Transcripts
ENST00000297565 ENSP00000297565
ENST00000435298 ENSP00000402862
ENST00000457907 ENSP00000414657
ENST00000520791
ENST00000523368 ENSP00000430041
ENST00000520722
ENST00000521044
ENST00000522510 ENSP00000430780
ENST00000520951 ENSP00000430074
ENST00000518199 ENSP00000429910
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0003676 nucleic acid binding
GO:0043565 sequence-specific DNA binding
GO:0046872 metal ion binding
Biological Process
GO:0000122 negative regulation of transcription from RNA polymerase II promoter
GO:0001656 metanephros development
GO:0001823 mesonephros development
GO:0002062 chondrocyte differentiation
GO:0008284 positive regulation of cell proliferation
GO:0009790 embryo development
GO:0010628 positive regulation of gene expression
GO:0030154 cell differentiation
GO:0030501 positive regulation of bone mineralization
GO:0033687 osteoblast proliferation
GO:0035115 embryonic forelimb morphogenesis
GO:0035116 embryonic hindlimb morphogenesis
GO:0036023 embryonic skeletal limb joint morphogenesis
GO:0042474 middle ear morphogenesis
GO:0042476 odontogenesis
GO:0042733 embryonic digit morphogenesis
GO:0045893 positive regulation of transcription, DNA-templated
GO:0045944 positive regulation of transcription from RNA polymerase II promoter
GO:0048704 embryonic skeletal system morphogenesis
GO:0048793 pronephros development
GO:0050679 positive regulation of epithelial cell proliferation
GO:0060021 palate development
GO:0060272 embryonic skeletal joint morphogenesis
GO:0060322 head development
GO:0060349 bone morphogenesis
GO:0061029 eyelid development in camera-type eye
GO:0072498 embryonic skeletal joint development
GO:2000543 positive regulation of gastrulation
Cellular Component
GO:0005634 nucleus
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000022330
View Gene Order
ENSBTAG00000013213
Not yet available
Cross-References
SwissProt
TrEMBL E5RH04 E5RH47
UniProt Splice Variant
Entrez Gene 116039
UniGene Hs.253247 Hs.630123
RefSeq NM_001142462 NM_001286841 NM_053001 XM_006716504
HUGO HGNC:15830
OMIM 611297
CCDS CCDS47901 CCDS47902 CCDS69520
HPRD 17806
IMGT
EMBL AC016877
GenPept
RNA Seq Atlas 116039

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca