Version 5.4
Homo sapiens Gene: PSG1
Summary
InnateDB Gene IDBG-306623.4
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol PSG1
Gene Name pregnancy specific beta-1-glycoprotein 1
Synonyms B1G1; CD66f; DHFRP2; FL-NCA-1/2; PBG1; PS-beta-C/D; PS-beta-G-1; PSBG-1; PSBG1; PSG95; PSGGA; PSGIIA; SP1
Species Homo sapiens
Ensembl Gene ENSG00000231924
Encoded Proteins
IDBP-54684
pregnancy specific beta-1-glycoprotein 1
IDBP-54688
pregnancy specific beta-1-glycoprotein 1
IDBP-294504
pregnancy specific beta-1-glycoprotein 1
IDBP-381214
pregnancy specific beta-1-glycoprotein 1
IDBP-765070
IDBP-763184
IDBP-765487
IDBP-764590
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary The human placenta is a multihormonal endocrine organ that produces hormones, enzymes, and other molecules that support fetal survival and development. Pregnancy-specific beta-1-glycoprotein (PSBG, PSG) is a major product of the syncytiotrophoblast, reaching concentrations of 100 to 290 mg/l at term in the serum of pregnant women (Horne et al., 1976 [PubMed 971765]). PSG is a member of the immunoglobulin (Ig) superfamily (Watanabe and Chou, 1988 [PubMed 3257488]; Streydio et al., 1988 [PubMed 3260773]).[supplied by OMIM, Oct 2009]
Gene Information
Type Protein coding
Genomic Location Chromosome 19:42866464-42879822
Strand Reverse strand
Band q13.2
Transcripts
ENST00000244296 ENSP00000244296
ENST00000312439 ENSP00000308970
ENST00000403380 ENSP00000385386
ENST00000436291 ENSP00000413041
ENST00000595124 ENSP00000472284
ENST00000602039
ENST00000601073
ENST00000595356 ENSP00000472610
ENST00000601456
ENST00000597058 ENSP00000470690
ENST00000595930 ENSP00000469575
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
Experimentally validated
Total 2 [view]
Protein-Protein 1 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
GO:0007565 female pregnancy
Cellular Component
GO:0005576 extracellular region
Orthologs
No orthologs found for this gene
Cross-References
SwissProt P11464
TrEMBL M0QY44 Q9UMI0
UniProt Splice Variant
Entrez Gene 5672
UniGene Hs.709192
RefSeq NM_001297773 XM_005259063 NM_001184825 NM_001184826 NM_006905 XM_005259069
HUGO HGNC:9514
OMIM 176390 176393
CCDS CCDS74380 CCDS12612 CCDS54275 CCDS59392
HPRD 01449
IMGT
EMBL AC005238 AH007517 BC022338 BC058285 CH471126 CR450329 J04539 M17908 M17909 M20879 M20881 M21822 M22437 M25385 M33663 M33664 M34715 M37397
GenPept AAA36511 AAA36513 AAA36515 AAA36517 AAA52590 AAA52591 AAA52601 AAA52602 AAA52603 AAA60196 AAA60204 AAA60960 AAC25488 AAC25489 AAC25490 AAD21020 AAH22338 AAH58285 CAG29325 EAW57156
RNA Seq Atlas 5669 5672

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca