Version 5.4
Homo sapiens Gene: PDHA2
Summary
InnateDB Gene IDBG-30771.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol PDHA2
Gene Name pyruvate dehydrogenase (lipoamide) alpha 2
Synonyms PDHAL
Species Homo sapiens
Ensembl Gene ENSG00000163114
Encoded Proteins
IDBP-30773
pyruvate dehydrogenase (lipoamide) alpha 2
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 4:95840019-95841474
Strand Forward strand
Band q22.3
Transcripts
ENST00000295266 ENSP00000295266
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 8 experimentally validated interaction(s) in this database.
Experimentally validated
Total 8 [view]
Protein-Protein 7 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 1 [view]
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0004739 pyruvate dehydrogenase (acetyl-transferring) activity
GO:0016624 oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
Biological Process
GO:0006006 glucose metabolic process
GO:0006090 pyruvate metabolic process
GO:0006096 glycolytic process
GO:0006099 tricarboxylic acid cycle
GO:0008152 metabolic process
GO:0055114 oxidation-reduction process
Cellular Component
GO:0005634 nucleus
GO:0005739 mitochondrion
GO:0005759 mitochondrial matrix
GO:0043231 intracellular membrane-bounded organelle
Orthologs
No orthologs found for this gene
Pathways
NETPATH
REACTOME
KEGG
hsa00010
Glycolysis / Gluconeogenesis pathway
hsa00620
Pyruvate metabolism pathway
hsa00020
Citrate cycle (TCA cycle) pathway
INOH
INOH website
Pyruvate metabolism pathway
PID NCI
Cross-References
SwissProt P29803
TrEMBL
UniProt Splice Variant
Entrez Gene 5161
UniGene Hs.131361
RefSeq NM_005390
HUGO HGNC:8807
OMIM 179061
CCDS CCDS3644
HPRD
IMGT
EMBL AK313872 BC030697 BC066953 BC094760 BC119656 BC119657 BC127637 BC127638 M86808
GenPept AAA60232 AAH30697 AAH66953 AAH94760 AAI19657 AAI19658 AAI27638 AAI27639 BAG36600
RNA Seq Atlas 5161

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca