Version 5.4
Homo sapiens Gene: LRCH1
Summary
InnateDB Gene IDBG-30838.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol LRCH1
Gene Name leucine-rich repeats and calponin homology (CH) domain containing 1
Synonyms CHDC1; NP81
Species Homo sapiens
Ensembl Gene ENSG00000136141
Encoded Proteins
IDBP-30840
leucine-rich repeats and calponin homology (CH) domain containing 1
IDBP-30844
leucine-rich repeats and calponin homology (CH) domain containing 1
IDBP-30846
leucine-rich repeats and calponin homology (CH) domain containing 1
IDBP-485447
leucine-rich repeats and calponin homology (CH) domain containing 1
IDBP-479557
leucine-rich repeats and calponin homology (CH) domain containing 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene encodes a protein with a leucine-rich repeat and a calponin homology domain. Polymorphism in this gene may be associated with susceptibililty to knee osteoarthritis. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Mar 2010]
Gene Information
Type Protein coding
Genomic Location Chromosome 13:46553168-46753040
Strand Forward strand
Band q14.13
Transcripts
ENST00000311191 ENSP00000308493
ENST00000389798 ENSP00000374448
ENST00000389797 ENSP00000374447
ENST00000443945
ENST00000463929 ENSP00000417121
ENST00000478412 ENSP00000419256
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 22 experimentally validated interaction(s) in this database.
Experimentally validated
Total 22 [view]
Protein-Protein 22 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
Cellular Component
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000068015
View Gene Order
ENSBTAG00000002959
Not yet available
Cross-References
SwissProt
TrEMBL C9J5B8 C9JWE0
UniProt Splice Variant
Entrez Gene 23143
UniGene Hs.507971 Hs.595310
RefSeq NM_001164211 NM_001164213 NM_015116
HUGO HGNC:20309
OMIM 610368
CCDS CCDS31972 CCDS53865 CCDS53866
HPRD 14307
IMGT
EMBL AL136958 AL138704 AL359880
GenPept
RNA Seq Atlas 23143

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca