Version 5.4
Homo sapiens Gene: TSPAN5
Summary
InnateDB Gene IDBG-30927.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol TSPAN5
Gene Name tetraspanin 5
Synonyms NET-4; NET4; TM4SF9; TSPAN-5
Species Homo sapiens
Ensembl Gene ENSG00000168785
Encoded Proteins
IDBP-30929
tetraspanin 5
IDBP-478231
tetraspanin 5
IDBP-482687
tetraspanin 5
IDBP-480524
tetraspanin 5
IDBP-481334
tetraspanin 5
IDBP-476697
tetraspanin 5
IDBP-481055
tetraspanin 5
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 4:98470367-98658629
Strand Reverse strand
Band q23
Transcripts
ENST00000305798 ENSP00000307701
ENST00000508798 ENSP00000421808
ENST00000505184 ENSP00000423916
ENST00000511753
ENST00000515440 ENSP00000422351
ENST00000509168
ENST00000515287 ENSP00000423504
ENST00000511651 ENSP00000426248
ENST00000511800 ENSP00000422548
ENST00000507167
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 4 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 4 [view]
Protein-Protein 2 [view]
Protein-DNA 2 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0019899 enzyme binding
Biological Process
GO:0045747 positive regulation of Notch signaling pathway
GO:0051604 protein maturation
GO:0090002 establishment of protein localization to plasma membrane
Cellular Component
GO:0005886 plasma membrane
GO:0016021 integral component of membrane
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000028152
View Gene Order
ENSBTAG00000012343
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.118118
RefSeq NM_005723
HUGO
OMIM
CCDS CCDS3646
HPRD 15513
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca