Homo sapiens Gene: TUBA1B
Summary
InnateDB Gene IDBG-31144.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol TUBA1B
Gene Name tubulin, alpha 1b
Synonyms K-ALPHA-1;
Species Homo sapiens
Ensembl Gene ENSG00000123416
Encoded Proteins
tubulin, alpha 1b
tubulin, alpha 1b
tubulin, alpha 1b
tubulin, alpha 1b
tubulin, alpha 1b
tubulin, alpha 1b
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 12:49127782-49131397
Strand Reverse strand
Band q13.12
Transcripts
ENST00000336023 ENSP00000336799
ENST00000332858
ENST00000547765 ENSP00000448045
ENST00000550367 ENSP00000449325
ENST00000551324
ENST00000549870 ENSP00000449460
ENST00000547476 ENSP00000449748
ENST00000552984 ENSP00000448648
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 103 experimentally validated interaction(s) in this database.
They are also associated with 8 interaction(s) predicted by orthology.
Experimentally validated
Total 103 [view]
Protein-Protein 101 [view]
Protein-DNA 2 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 8 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003725 double-stranded RNA binding
GO:0003924 GTPase activity
GO:0005198 structural molecule activity
GO:0005200 structural constituent of cytoskeleton
GO:0005515 protein binding
GO:0005525 GTP binding
Biological Process
GO:0000226 microtubule cytoskeleton organization
GO:0006184 GTP catabolic process
GO:0006457 protein folding
GO:0007017 microtubule-based process
GO:0030705 cytoskeleton-dependent intracellular transport
GO:0044267 cellular protein metabolic process
GO:0051084 'de novo' posttranslational protein folding
GO:0051258 protein polymerization
GO:0051301 cell division
GO:0071353 cellular response to interleukin-4
Cellular Component
GO:0005874 microtubule
GO:0005881 cytoplasmic microtubule
GO:0043234 protein complex
GO:0070062 extracellular vesicular exosome
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
Method
Confidence
Comments
SSD Ortholog
Ortholog supports species divergence
Not yet available
SSD Ortholog
Ortholog supports species divergence
Pathways
NETPATH
REACTOME
Formation of tubulin folding intermediates by CCT/TriC pathway
Protein folding pathway
Post-chaperonin tubulin folding pathway pathway
MHC class II antigen presentation pathway
Kinesins pathway
Developmental Biology pathway
Signaling by Hedgehog pathway
Recruitment of NuMA to mitotic centrosomes pathway
Recruitment of mitotic centrosome proteins and complexes pathway
Transport of connexons to the plasma membrane pathway
Axon guidance pathway
Signal Transduction pathway
Separation of Sister Chromatids pathway
Hedgehog 'off' state pathway
Gap junction trafficking pathway
Chaperonin-mediated protein folding pathway
Mitotic Prometaphase pathway
Cell Cycle pathway
Recycling pathway of L1 pathway
Metabolism of proteins pathway
Adaptive Immune System pathway
Immune System pathway
Cooperation of Prefoldin and TriC/CCT in actin and tubulin folding pathway
Gap junction assembly pathway
M Phase pathway
Mitotic Anaphase pathway
Centrosome maturation pathway
G2/M Transition pathway
Translocation of GLUT4 to the plasma membrane pathway
L1CAM interactions pathway
Factors involved in megakaryocyte development and platelet production pathway
Cell Cycle, Mitotic pathway
Mitotic G2-G2/M phases pathway
Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane pathway
Resolution of Sister Chromatid Cohesion pathway
Gap junction trafficking and regulation pathway
Hemostasis pathway
Membrane Trafficking pathway
Mitotic Metaphase and Anaphase pathway
KEGG
Phagosome pathway
Gap junction pathway
Pathogenic Escherichia coli infection pathway
INOH
PID BIOCARTA
PID NCI
Signaling events mediated by HDAC Class II
Signaling events mediated by PRL
Signaling events mediated by HDAC Class III
Cross-References
SwissProt
TrEMBL F8VRK0 F8VXZ7
UniProt Splice Variant
Entrez Gene 10376
UniGene Hs.524390 Hs.724618 Hs.731075
RefSeq NM_006082
HUGO HGNC:18809
OMIM 602530
CCDS CCDS31792
HPRD 03960
IMGT
EMBL AC010173 AC011603
GenPept
RNA Seq Atlas 10376