Version 5.4
Homo sapiens Gene: SPZ1
Summary
InnateDB Gene IDBG-31318.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol SPZ1
Gene Name spermatogenic leucine zipper 1
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000164299
Encoded Proteins
IDBP-31320
spermatogenic leucine zipper 1
IDBP-477238
spermatogenic leucine zipper 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene encodes a bHLH-zip transcription factor which functions in the mitogen-activate protein kinase (MAPK) signaling pathway. Because of its role in the upregulation of cell proliferation and tumorigenesis, this gene may serve as a target for Ras-induced tumor treatments. [provided by RefSeq, Oct 2011]
Gene Information
Type Protein coding
Genomic Location Chromosome 5:80319625-80321842
Strand Forward strand
Band q14.1
Transcripts
ENST00000296739 ENSP00000369611
ENST00000511881 ENSP00000426530
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 5 experimentally validated interaction(s) in this database.
Experimentally validated
Total 5 [view]
Protein-Protein 5 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0003677 DNA binding
Biological Process
GO:0006351 transcription, DNA-templated
GO:0006355 regulation of transcription, DNA-templated
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000046957
View Gene Order
ENSBTAG00000024593
Not yet available
Cross-References
SwissProt
TrEMBL D6RFL8
UniProt Splice Variant
Entrez Gene 84654
UniGene Hs.519403
RefSeq NM_032567
HUGO HGNC:30721
OMIM
CCDS CCDS43336
HPRD 15440
IMGT
EMBL AC026410
GenPept
RNA Seq Atlas 84654

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca