Version 5.4
Homo sapiens Gene: KCNH3
Summary
InnateDB Gene IDBG-31534.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol KCNH3
Gene Name potassium voltage-gated channel, subfamily H (eag-related), member 3
Synonyms BEC1; ELK2; Kv12.2
Species Homo sapiens
Ensembl Gene ENSG00000135519
Encoded Proteins
IDBP-31536
potassium voltage-gated channel, subfamily H (eag-related), member 3
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 12:49539157-49558308
Strand Forward strand
Band q13.12
Transcripts
ENST00000257981 ENSP00000257981
ENST00000550434
ENST00000551415
ENST00000548675
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0000155 phosphorelay sensor kinase activity
GO:0004871 signal transducer activity
GO:0005216 ion channel activity
GO:0005249 voltage-gated potassium channel activity
GO:0005515 protein binding
Biological Process
GO:0000160 phosphorelay signal transduction system
GO:0006355 regulation of transcription, DNA-templated
GO:0006811 ion transport
GO:0006813 potassium ion transport
GO:0007165 signal transduction
GO:0007268 synaptic transmission
GO:0023014 signal transduction by phosphorylation
GO:0034765 regulation of ion transmembrane transport
GO:0042391 regulation of membrane potential
GO:0055085 transmembrane transport
GO:0071805 potassium ion transmembrane transport
Cellular Component
GO:0005886 plasma membrane
GO:0005887 integral component of plasma membrane
GO:0016020 membrane
GO:0016021 integral component of membrane
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000037579
View Gene Order
ENSBTAG00000019277
Not yet available
Pathways
NETPATH
REACTOME
REACT_75770
Voltage gated Potassium channels pathway
REACT_13685
Neuronal System pathway
REACT_75908
Potassium Channels pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt Q9ULD8
TrEMBL Q8N500
UniProt Splice Variant
Entrez Gene 23416
UniGene Hs.64064
RefSeq NM_012284 XM_005268752 XM_005268753 XM_006719313
HUGO HGNC:6252
OMIM 604527
CCDS CCDS8786
HPRD 05164
IMGT
EMBL AB022696 AB033108 BC033141
GenPept AAH33141 BAA83590 BAA86596
RNA Seq Atlas 23416

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca