Homo sapiens Gene: ADAMTS17
Summary
InnateDB Gene IDBG-31950.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol ADAMTS17
Gene Name ADAM metallopeptidase with thrombospondin type 1 motif, 17
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000140470
Encoded Proteins
ADAM metallopeptidase with thrombospondin type 1 motif, 17
ADAM metallopeptidase with thrombospondin type 1 motif, 17
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) protein family. ADAMTS family members share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The protein encoded by this gene has a high sequence similarity to the protein encoded by ADAMTS19, another family member. The function of this protein has not been determined. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 15:99971589-100342005
Strand Reverse strand
Band q26.3
Transcripts
ENST00000268070 ENSP00000268070
ENST00000378898
ENST00000557896
ENST00000559976
ENST00000560486
ENST00000558960 ENSP00000453604
ENST00000561355 ENSP00000458005
ENST00000558930
ENST00000568565 ENSP00000456161
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0004222 metalloendopeptidase activity
GO:0008233 peptidase activity
GO:0008270 zinc ion binding
Biological Process
GO:0006508 proteolysis
Cellular Component
GO:0005578 proteinaceous extracellular matrix
GO:0031012 extracellular matrix
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
Not yet available
Pathways
NETPATH
REACTOME
Post-translational protein modification pathway
O-linked glycosylation pathway
Metabolism of proteins pathway
O-glycosylation of TSR domain-containing proteins pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt
TrEMBL H0YMH1
UniProt Splice Variant
Entrez Gene 170691
UniGene Hs.513200
RefSeq NM_139057
HUGO HGNC:17109
OMIM 607511
CCDS CCDS10383
HPRD 06332
IMGT
EMBL AC015723 AC022710 AC084855 AC113187
GenPept
RNA Seq Atlas 170691