Homo sapiens Gene: ADAMTS17
Summary
InnateDB Gene IDBG-31950.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol ADAMTS17
Gene Name ADAM metallopeptidase with thrombospondin type 1 motif, 17
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000140470
Encoded Proteins
ADAM metallopeptidase with thrombospondin type 1 motif, 17
ADAM metallopeptidase with thrombospondin type 1 motif, 17
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) protein family. ADAMTS family members share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The protein encoded by this gene has a high sequence similarity to the protein encoded by ADAMTS19, another family member. The function of this protein has not been determined. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 15:99971589-100342005
Strand Reverse strand
Band q26.3
Transcripts
ENST00000268070 ENSP00000268070
ENST00000378898
ENST00000557896
ENST00000559976
ENST00000560486
ENST00000558960 ENSP00000453604
ENST00000561355 ENSP00000458005
ENST00000558930
ENST00000568565 ENSP00000456161
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0004222 metalloendopeptidase activity
GO:0008233 peptidase activity
GO:0008270 zinc ion binding
Biological Process
GO:0006508 proteolysis
Cellular Component
GO:0005578 proteinaceous extracellular matrix
GO:0031012 extracellular matrix
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
Method
Confidence
Comments
SSD Ortholog
Ortholog supports species divergence
Not yet available
SSD Ortholog
Ortholog supports species divergence
Pathways
NETPATH
REACTOME
Post-translational protein modification pathway
O-linked glycosylation pathway
Metabolism of proteins pathway
O-glycosylation of TSR domain-containing proteins pathway
KEGG
INOH
PID BIOCARTA
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.513200
RefSeq NM_139057
HUGO
OMIM
CCDS CCDS10383
HPRD 06332
IMGT
EMBL
GenPept
RNA Seq Atlas