Version 5.4
Homo sapiens Gene: TMBIM6
Summary
InnateDB Gene IDBG-31960.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol TMBIM6
Gene Name transmembrane BAX inhibitor motif containing 6
Synonyms BAXI1; BI-1; TEGT
Species Homo sapiens
Ensembl Gene ENSG00000139644
Encoded Proteins
IDBP-31962
transmembrane BAX inhibitor motif containing 6
IDBP-240432
transmembrane BAX inhibitor motif containing 6
IDBP-374641
transmembrane BAX inhibitor motif containing 6
IDBP-586788
transmembrane BAX inhibitor motif containing 6
IDBP-585154
transmembrane BAX inhibitor motif containing 6
IDBP-591921
transmembrane BAX inhibitor motif containing 6
IDBP-589569
transmembrane BAX inhibitor motif containing 6
IDBP-591714
transmembrane BAX inhibitor motif containing 6
IDBP-595575
transmembrane BAX inhibitor motif containing 6
IDBP-599797
transmembrane BAX inhibitor motif containing 6
IDBP-598404
transmembrane BAX inhibitor motif containing 6
IDBP-593823
transmembrane BAX inhibitor motif containing 6
IDBP-594622
transmembrane BAX inhibitor motif containing 6
IDBP-589891
transmembrane BAX inhibitor motif containing 6
IDBP-598208
transmembrane BAX inhibitor motif containing 6
IDBP-591450
transmembrane BAX inhibitor motif containing 6
IDBP-599863
transmembrane BAX inhibitor motif containing 6
IDBP-599592
transmembrane BAX inhibitor motif containing 6
IDBP-593995
transmembrane BAX inhibitor motif containing 6
IDBP-595689
transmembrane BAX inhibitor motif containing 6
IDBP-593418
transmembrane BAX inhibitor motif containing 6
IDBP-597382
transmembrane BAX inhibitor motif containing 6
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 12:49707725-49764934
Strand Forward strand
Band q13.12
Transcripts
ENST00000267115 ENSP00000267115
ENST00000395006 ENSP00000378454
ENST00000423828 ENSP00000389277
ENST00000548809 ENSP00000449000
ENST00000548589
ENST00000551154 ENSP00000450417
ENST00000546796 ENSP00000450159
ENST00000549966 ENSP00000446668
ENST00000547832 ENSP00000448269
ENST00000547187 ENSP00000447400
ENST00000548894 ENSP00000447074
ENST00000546914 ENSP00000448612
ENST00000552635 ENSP00000450050
ENST00000552699 ENSP00000446734
ENST00000549445 ENSP00000449904
ENST00000546885
ENST00000550951 ENSP00000449421
ENST00000549385 ENSP00000448036
ENST00000548713 ENSP00000447888
ENST00000548201 ENSP00000450265
ENST00000550445 ENSP00000449907
ENST00000549130 ENSP00000450305
ENST00000552370 ENSP00000450158
ENST00000547798 ENSP00000447030
ENST00000553022
ENST00000547013
ENST00000550040
ENST00000549471
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 11 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
Experimentally validated
Total 11 [view]
Protein-Protein 7 [view]
Protein-DNA 4 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 2 [view]
Gene Ontology

Molecular Function
Accession GO Term
Biological Process
GO:0006915 apoptotic process
GO:0006986 response to unfolded protein
GO:0032469 endoplasmic reticulum calcium ion homeostasis
GO:0043066 negative regulation of apoptotic process
GO:0070059 intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress
Cellular Component
GO:0005634 nucleus
GO:0005783 endoplasmic reticulum
GO:0005789 endoplasmic reticulum membrane
GO:0005887 integral component of plasma membrane
GO:0016020 membrane
GO:0016021 integral component of membrane
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000023010
View Gene Order
ENSBTAG00000018588
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.35052 Hs.618803 Hs.731576
RefSeq NM_001098576 NM_003217 XM_005269126
HUGO
OMIM
CCDS CCDS31797 CCDS44875
HPRD 02851
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca