Version 5.4
Homo sapiens Gene: MT2A
Summary
InnateDB Gene IDBG-32154.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol MT2A
Gene Name metallothionein 2A
Synonyms MT2
Species Homo sapiens
Ensembl Gene ENSG00000125148
Encoded Proteins
IDBP-32156
metallothionein 2A
IDBP-751263
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 16:56608199-56609497
Strand Forward strand
Band q13
Transcripts
ENST00000245185 ENSP00000245185
ENST00000561491 ENSP00000456804
ENST00000563985
ENST00000562017
ENST00000567300
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 27 experimentally validated interaction(s) in this database.
Experimentally validated
Total 27 [view]
Protein-Protein 22 [view]
Protein-DNA 5 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0008144 drug binding
GO:0008270 zinc ion binding
GO:0046872 metal ion binding
Biological Process
GO:0006878 cellular copper ion homeostasis
GO:0019221 cytokine-mediated signaling pathway
GO:0035690 cellular response to drug
GO:0036016 cellular response to interleukin-3
GO:0036018 cellular response to erythropoietin
GO:0045926 negative regulation of growth
GO:0060333 interferon-gamma-mediated signaling pathway
GO:0071294 cellular response to zinc ion
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0048471 perinuclear region of cytoplasm
Orthologs
No orthologs found for this gene
Pathways
NETPATH
REACTOME
REACT_25078
Interferon gamma signaling pathway
REACT_75790
Cytokine Signaling in Immune system pathway
REACT_25229
Interferon Signaling pathway
REACT_6900
Immune System pathway
KEGG
INOH
PID NCI
ap1_pathway
AP-1 transcription factor network
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene
RefSeq NM_005953
HUGO
OMIM
CCDS CCDS10763
HPRD 08863
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca