Version 5.4
| Homo sapiens Gene: FBXW12 | |||||||||||||
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| Summary | |||||||||||||
| InnateDB Gene | IDBG-32446.6 | ||||||||||||
| Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||||||
| Gene Symbol | FBXW12 | ||||||||||||
| Gene Name | F-box and WD repeat domain containing 12 | ||||||||||||
| Synonyms | |||||||||||||
| Species | Homo sapiens | ||||||||||||
| Ensembl Gene | ENSG00000164049 | ||||||||||||
| Encoded Proteins |
F-box and WD repeat domain containing 12
F-box and WD repeat domain containing 12
F-box and WD repeat domain containing 12
F-box and WD repeat domain containing 12
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| Protein Structure |
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| Useful resources | Stemformatics EHFPI ImmGen | ||||||||||||
| Entrez Gene | |||||||||||||
| Summary |
Members of the F-box protein family, such as FBXW12, are characterized by an approximately 40-amino acid F-box motif. SCF complexes, formed by SKP1 (MIM 601434), cullin (see CUL1; MIM 603034), and F-box proteins, act as protein-ubiquitin ligases. F-box proteins interact with SKP1 through the F box, and they interact with ubiquitination targets through other protein interaction domains (Jin et al., 2004 [PubMed 15520277]).[supplied by OMIM, Mar 2008] |
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| Gene Information | |||||||||||||
| Type | Protein coding | ||||||||||||
| Genomic Location | Chromosome 3:48372219-48401259 | ||||||||||||
| Strand | Forward strand | ||||||||||||
| Band | p21.31 | ||||||||||||
| Transcripts |
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| Interactions | |||||||||||||
| Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
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| Gene Ontology | |||||||||||||
Molecular Function |
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| Biological Process |
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| Cellular Component |
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| Orthologs | |||||||||||||
| No orthologs found for this gene | |||||||||||||
| Cross-References | |||||||||||||
| SwissProt | Q6X9E4 | ||||||||||||
| TrEMBL | C9JK86 | ||||||||||||
| UniProt Splice Variant | |||||||||||||
| Entrez Gene | 285231 | ||||||||||||
| UniGene | Hs.288793 | ||||||||||||
| RefSeq | NM_207102 NM_001159927 NM_001159929 | ||||||||||||
| HUGO | HGNC:20729 | ||||||||||||
| OMIM | 609075 | ||||||||||||
| CCDS | CCDS2764 CCDS54577 CCDS54578 | ||||||||||||
| HPRD | 16428 | ||||||||||||
| IMGT | |||||||||||||
| EMBL | AC104448 AY247969 BC101304 BC101305 | ||||||||||||
| GenPept | AAI01305 AAI01306 AAP75562 | ||||||||||||
| RNA Seq Atlas | 285231 | ||||||||||||