Version 5.4
Homo sapiens Gene: EBAG9
Summary
InnateDB Gene IDBG-32695.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol EBAG9
Gene Name estrogen receptor binding site associated, antigen, 9
Synonyms EB9; PDAF
Species Homo sapiens
Ensembl Gene ENSG00000147654
Encoded Proteins
IDBP-32697
estrogen receptor binding site associated, antigen, 9
IDBP-238849
estrogen receptor binding site associated, antigen, 9
IDBP-592944
estrogen receptor binding site associated, antigen, 9
IDBP-590338
estrogen receptor binding site associated, antigen, 9
IDBP-598069
estrogen receptor binding site associated, antigen, 9
IDBP-585945
estrogen receptor binding site associated, antigen, 9
IDBP-598133
estrogen receptor binding site associated, antigen, 9
IDBP-807829
estrogen receptor binding site associated, antigen, 9
IDBP-807831
estrogen receptor binding site associated, antigen, 9
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene was identified as an estrogen-responsive gene. Regulation of transcription by estrogen is mediated by estrogen receptor which binds to the estrogen-responsive element (ERE) found in the 5'-flanking region of this gene. The encoded protein is a tumor-associated antigen that is expressed at high frequency in a variety of cancers. Two transcript variants differing in the 5' UTR, but encoding the same protein, have been identified for this gene. [provided by RefSeq, Jul 2008]
This gene was identified as an estrogen-responsive gene. Regulation of transcription by estrogen is mediated by estrogen receptor, which binds to the estrogen-responsive element found in the 5\'-flanking region of this gene. The encoded protein is a tumor-associated antigen that is expressed at high frequency in a variety of cancers. Alternate splicing results in multiple transcript variants. A pseudogene of this gene has been defined on chromosome 10. [provided by RefSeq, Jul 2013]
Gene Information
Type Protein coding
Genomic Location Chromosome 8:109539711-109565996
Strand Forward strand
Band q23.2
Transcripts
ENST00000337573 ENSP00000337675
ENST00000395785 ENSP00000379131
ENST00000529502
ENST00000529931 ENSP00000435687
ENST00000527709 ENSP00000437214
ENST00000530629 ENSP00000434878
ENST00000534318 ENSP00000435689
ENST00000531677 ENSP00000432082
ENST00000620557 ENSP00000477645
ENST00000614147 ENSP00000477734
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 7 experimentally validated interaction(s) in this database.
Experimentally validated
Total 7 [view]
Protein-Protein 3 [view]
Protein-DNA 4 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0016505 peptidase activator activity involved in apoptotic process
Biological Process
GO:0001558 regulation of cell growth
GO:0006915 apoptotic process
Cellular Component
GO:0000139 Golgi membrane
GO:0005794 Golgi apparatus
GO:0005886 plasma membrane
GO:0005925 focal adhesion
GO:0016021 integral component of membrane
GO:0030141 secretory granule
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000022339
View Gene Order
ENSBTAG00000037571
Not yet available
Pathways
NETPATH
REACTOME
KEGG
INOH
PID NCI
era_genomic_pathway
Validated nuclear estrogen receptor alpha network
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.409368 Hs.632960
RefSeq NM_001278938 NM_004215 NM_198120
HUGO
OMIM
CCDS CCDS6313
HPRD 05775
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca