Homo sapiens Gene: LETMD1
Summary
InnateDB Gene IDBG-32999.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol LETMD1
Gene Name LETM1 domain containing 1
Synonyms 1110019O13Rik; HCCR-1; HCCR-2; HCCR1; HCRR-2;
Species Homo sapiens
Ensembl Gene ENSG00000050426
Encoded Proteins
LETM1 domain containing 1
LETM1 domain containing 1
LETM1 domain containing 1
LETM1 domain containing 1
LETM1 domain containing 1
LETM1 domain containing 1
LETM1 domain containing 1
LETM1 domain containing 1
LETM1 domain containing 1
LETM1 domain containing 1
LETM1 domain containing 1
LETM1 domain containing 1
LETM1 domain containing 1
LETM1 domain containing 1
LETM1 domain containing 1
LETM1 domain containing 1
LETM1 domain containing 1
LETM1 domain containing 1
LETM1 domain containing 1
LETM1 domain containing 1
LETM1 domain containing 1
LETM1 domain containing 1
LETM1 domain containing 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene encodes a mitochondrial outer membrane protein. It has a potential role in tumorigenesis, which may result from negative regulation of the p53 tumor suppressor gene. Alternatively spliced transcript variants have been noted for this gene. [provided by RefSeq, Aug 2011]
Gene Information
Type Protein coding
Genomic Location Chromosome 12:51047962-51060424
Strand Forward strand
Band q13.12
Transcripts
ENST00000262055 ENSP00000262055
ENST00000380135 ENSP00000369478
ENST00000418425 ENSP00000389903
ENST00000551477 ENSP00000446862
ENST00000547318 ENSP00000448442
ENST00000552430
ENST00000553175
ENST00000550755 ENSP00000449681
ENST00000550446
ENST00000550929 ENSP00000450163
ENST00000547029
ENST00000550442 ENSP00000448110
ENST00000549340 ENSP00000449896
ENST00000548390
ENST00000546992
ENST00000551261 ENSP00000448800
ENST00000548209 ENSP00000450275
ENST00000548251 ENSP00000447166
ENST00000550715
ENST00000550814 ENSP00000448222
ENST00000547660 ENSP00000450391
ENST00000547555 ENSP00000450390
ENST00000548401 ENSP00000450082
ENST00000549686 ENSP00000447420
ENST00000547008 ENSP00000447419
ENST00000547877
ENST00000550100 ENSP00000447047
ENST00000552739 ENSP00000450333
ENST00000548516
ENST00000552645
ENST00000547256 ENSP00000446551
ENST00000552433
ENST00000546814
ENST00000551931 ENSP00000450251
ENST00000550274
ENST00000553043 ENSP00000446967
ENST00000549395
ENST00000623495
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.
Experimentally validated
Total 3 [view]
Protein-Protein 2 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
Cellular Component
GO:0005739 mitochondrion
GO:0005741 mitochondrial outer membrane
GO:0016021 integral component of membrane
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
Method
Confidence
Comments
SSD Ortholog
Ortholog supports species divergence
Not yet available
SSD Ortholog
Ortholog supports species divergence
Cross-References
SwissProt
TrEMBL F8VR35 F8VVQ3
UniProt Splice Variant
Entrez Gene 25875
UniGene Hs.655272
RefSeq NM_015416 NM_001243689 NM_001300765 XM_006719334 XM_006719340 XM_006719337
HUGO HGNC:24241
OMIM
CCDS CCDS8806 CCDS58231 CCDS73469
HPRD 09978
IMGT
EMBL AC087884
GenPept
RNA Seq Atlas 25875