Version 5.4
Homo sapiens Gene: DNAJB1
Summary
InnateDB Gene IDBG-33491.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol DNAJB1
Gene Name DnaJ (Hsp40) homolog, subfamily B, member 1
Synonyms Hdj1; Hsp40; HSPF1; RSPH16B; Sis1
Species Homo sapiens
Ensembl Gene ENSG00000132002
Encoded Proteins
IDBP-33493
DnaJ (Hsp40) homolog, subfamily B, member 1
IDBP-596780
DnaJ (Hsp40) homolog, subfamily B, member 1
IDBP-760558
IDBP-765887
IDBP-760217
IDBP-762896
IDBP-764906
IDBP-761601
IDBP-765839
IDBP-764129
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 19:14514770-14529770
Strand Reverse strand
Band p13.12
Transcripts
ENST00000254322 ENSP00000254322
ENST00000396969 ENSP00000444212
ENST00000601533 ENSP00000471798
ENST00000594099 ENSP00000470460
ENST00000595139 ENSP00000469221
ENST00000596075 ENSP00000471603
ENST00000601087
ENST00000596853 ENSP00000470063
ENST00000598235 ENSP00000471073
ENST00000598692 ENSP00000472886
ENST00000595992 ENSP00000470596
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 77 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
Experimentally validated
Total 77 [view]
Protein-Protein 74 [view]
Protein-DNA 3 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 2 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0001671 ATPase activator activity
GO:0005515 protein binding
GO:0030544 Hsp70 protein binding
GO:0051082 unfolded protein binding
GO:0051087 chaperone binding
GO:0051117 ATPase binding
Biological Process
GO:0006457 protein folding
GO:0006986 response to unfolded protein
GO:0032781 positive regulation of ATPase activity
GO:0051085 chaperone mediated protein folding requiring cofactor
GO:0070389 chaperone cofactor-dependent protein refolding
GO:0090084 negative regulation of inclusion body assembly
Cellular Component
GO:0005634 nucleus
GO:0005730 nucleolus
GO:0005829 cytosol
GO:0070062 extracellular vesicular exosome
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000005483
View Gene Order
ENSBTAG00000016874
Not yet available
Pathways
NETPATH
NetPath_11
TCR pathway
REACTOME
REACT_120956
Cellular responses to stress pathway
REACT_200780
Regulation of HSF1-mediated heat shock response pathway
REACT_200624
Attenuation phase pathway
REACT_200775
HSF1-dependent transactivation pathway
REACT_200819
Cellular response to heat stress pathway
KEGG
hsa04141
Protein processing in endoplasmic reticulum pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL M0QYT3 M0QZD0 M0R128 M0R1D6 M0R2Y8
UniProt Splice Variant
Entrez Gene 3337
UniGene Hs.515210
RefSeq NM_001300914 NM_006145 XM_006722733 XM_006722734 XM_006722735 XM_006722736
HUGO HGNC:5270
OMIM 604572
CCDS CCDS12312 CCDS74295
HPRD 05198
IMGT
EMBL AC009004 AC012318
GenPept
RNA Seq Atlas 3337

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca