Version 5.4
Homo sapiens Gene: NCR3LG1
Summary
InnateDB Gene IDBG-33812.7
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol NCR3LG1
Gene Name natural killer cell cytotoxicity receptor 3 ligand 1
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000188211
Encoded Proteins
IDBP-33814
B7 homolog 6
IDBP-595353
B7 homolog 6
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary B7H6 belongs to the B7 family (see MIM 605402) and is selectively expressed on tumor cells. Interaction of B7H6 with NKp30 (NCR3; MIM 611550) results in natural killer (NK) cell activation and cytotoxicity (Brandt et al., 2009 [PubMed 19528259]).[supplied by OMIM, Jan 2011]
Gene Information
Type Protein coding
Genomic Location Chromosome 11:17351726-17377341
Strand Forward strand
Band p15.1
Transcripts
ENST00000338965 ENSP00000341637
ENST00000530403 ENSP00000434394
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.
Experimentally validated
Total 3 [view]
Protein-Protein 3 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005198 structural molecule activity
GO:0005515 protein binding
Biological Process
Cellular Component
GO:0005886 plasma membrane
GO:0016021 integral component of membrane
GO:0019028 viral capsid
Orthologs
No orthologs found for this gene
Cross-References
SwissProt Q68D85
TrEMBL
UniProt Splice Variant
Entrez Gene 374383
UniGene Hs.146274
RefSeq NM_001202439
HUGO HGNC:42400
OMIM 613714
CCDS CCDS55748
HPRD 16820
IMGT
EMBL AC124798 BC136797 BC136800 BX537685 CR749521
GenPept CAD97811 CAH18335
RNA Seq Atlas 374383

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca