Version 5.4
Homo sapiens Gene: DHRS4
Summary
InnateDB Gene IDBG-3418.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol DHRS4
Gene Name dehydrogenase/reductase (SDR family) member 4
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000157326
Encoded Proteins
IDBP-3420
dehydrogenase/reductase (SDR family) member 4
IDBP-236138
dehydrogenase/reductase (SDR family) member 4
IDBP-236140
dehydrogenase/reductase (SDR family) member 4
IDBP-591780
dehydrogenase/reductase (SDR family) member 4
IDBP-595579
dehydrogenase/reductase (SDR family) member 4
IDBP-592568
dehydrogenase/reductase (SDR family) member 4
IDBP-600720
dehydrogenase/reductase (SDR family) member 4
IDBP-599822
dehydrogenase/reductase (SDR family) member 4
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 14:23953586-23969279
Strand Forward strand
Band q11.2
Transcripts
ENST00000313250 ENSP00000326219
ENST00000397075 ENSP00000380265
ENST00000397074 ENSP00000380264
ENST00000558263 ENSP00000453367
ENST00000543741 ENSP00000440508
ENST00000559632 ENSP00000453983
ENST00000558581 ENSP00000452645
ENST00000559975 ENSP00000454099
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 8 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 8 [view]
Protein-Protein 6 [view]
Protein-DNA 2 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0000253 3-keto sterol reductase activity
GO:0004090 carbonyl reductase (NADPH) activity
GO:0005102 receptor binding
GO:0016491 oxidoreductase activity
GO:0016655 oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor
GO:0018455 alcohol dehydrogenase [NAD(P)+] activity
Biological Process
GO:0006066 alcohol metabolic process
GO:0008152 metabolic process
GO:0008202 steroid metabolic process
GO:0042180 cellular ketone metabolic process
GO:0051262 protein tetramerization
GO:0055114 oxidation-reduction process
Cellular Component
GO:0005634 nucleus
GO:0005739 mitochondrion
GO:0005777 peroxisome
GO:0005778 peroxisomal membrane
GO:0031965 nuclear membrane
GO:0043231 intracellular membrane-bounded organelle
GO:0070062 extracellular vesicular exosome
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000022210
View Gene Order
ENSBTAG00000017665
Not yet available
Pathways
NETPATH
REACTOME
KEGG
hsa00830
Retinol metabolism pathway
hsa04146
Peroxisome pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene
RefSeq NM_001282987 NM_001282988 NM_001282989 NM_001282990 NM_001282991 NM_021004 XM_006720006 XM_006720246
HUGO
OMIM
CCDS CCDS61408 CCDS61409 CCDS61410 CCDS61411 CCDS61412 CCDS9605
HPRD 07484
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca