Homo sapiens Gene: MRPL13
Summary
InnateDB Gene IDBG-34268.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol MRPL13
Gene Name mitochondrial ribosomal protein L13
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000172172
Encoded Proteins
mitochondrial ribosomal protein L13
mitochondrial ribosomal protein L13
mitochondrial ribosomal protein L13
mitochondrial ribosomal protein L13
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 8:120380761-120445402
Strand Reverse strand
Band q24.12
Transcripts
ENST00000306185 ENSP00000306548
ENST00000521648 ENSP00000428229
ENST00000518696 ENSP00000428867
ENST00000522717
ENST00000518918 ENSP00000430545
ENST00000520677
ENST00000613356
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 37 experimentally validated interaction(s) in this database.
Experimentally validated
Total 37 [view]
Protein-Protein 37 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0003735 structural constituent of ribosome
GO:0005515 protein binding
GO:0044822 poly(A) RNA binding
Biological Process
GO:0006412 translation
Cellular Component
GO:0005739 mitochondrion
GO:0005761 mitochondrial ribosome
GO:0005762 mitochondrial large ribosomal subunit
GO:0005840 ribosome
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
Method
Confidence
Comments
SSD Ortholog
Ortholog supports species divergence
Not yet available
SSD Ortholog
Ortholog supports species divergence
Pathways
NETPATH
REACTOME
Organelle biogenesis and maintenance pathway
Mitochondrial translation pathway
Mitochondrial translation initiation pathway
Mitochondrial translation termination pathway
Mitochondrial translation elongation pathway
KEGG
Ribosome pathway
INOH
PID BIOCARTA
PID NCI
Cross-References
SwissProt Q9BYD1
TrEMBL E5RJI7 H0YAX3
UniProt Splice Variant
Entrez Gene 28998
UniGene Hs.333823
RefSeq NM_014078
HUGO HGNC:14278
OMIM 610200
CCDS CCDS6332
HPRD 14740
IMGT
EMBL AB049640 AC107877 AF112214 AK311924 BC009190 BC021744 CH471060
GenPept AAF17202 AAH09190 AAH21744 BAB40845 BAG34865 EAW92004
RNA Seq Atlas 28998