Version 5.4
Homo sapiens Gene: SLC5A10
Summary
InnateDB Gene IDBG-34399.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol SLC5A10
Gene Name solute carrier family 5 (sodium/glucose cotransporter), member 10
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000154025
Encoded Proteins
IDBP-34401
solute carrier family 5 (sodium/glucose cotransporter), member 10
IDBP-239123
solute carrier family 5 (sodium/glucose cotransporter), member 10
IDBP-239125
solute carrier family 5 (sodium/glucose cotransporter), member 10
IDBP-239127
solute carrier family 5 (sodium/glucose cotransporter), member 10
IDBP-372177
solute carrier family 5 (sodium/glucose cotransporter), member 10
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene is a member of the sodium/glucose transporter family. Members of this family are sodium-dependent transporters and can be divided into two subfamilies based on sequence homology, one that co-transports sugars and the second that transports molecules such as ascorbate, choline, iodide, lipoate, monocaroboxylates, and pantothenate. The protein encoded by this gene has the highest affinity for mannose and has been reported to be most highly expressed in the kidney. This protein may function as a kidney-specific, sodium-dependent mannose and fructose co-transporter. Alternative splicing results in multiple transcript variants that encode different protein isoforms. [provided by RefSeq, Jul 2012]
Gene Information
Type Protein coding
Genomic Location Chromosome 17:18950345-19022595
Strand Forward strand
Band p11.2
Transcripts
ENST00000317977 ENSP00000324346
ENST00000395647 ENSP00000379008
ENST00000395645 ENSP00000379007
ENST00000395643 ENSP00000379005
ENST00000417251 ENSP00000401875
ENST00000584658
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0005215 transporter activity
Biological Process
GO:0006810 transport
GO:0006814 sodium ion transport
GO:0055085 transmembrane transport
Cellular Component
GO:0005886 plasma membrane
GO:0016020 membrane
GO:0016021 integral component of membrane
GO:0070062 extracellular vesicular exosome
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000042371
View Gene Order
ENSBTAG00000003700
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.462418
RefSeq NM_001042450 NM_001270648 NM_001270649 NM_001282417 NM_152351 XM_006721451
HUGO
OMIM
CCDS CCDS11201 CCDS42275 CCDS59277 CCDS59278 CCDS74008
HPRD 15394
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca