Homo sapiens Gene: KRT85
Summary
InnateDB Gene IDBG-34426.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol KRT85
Gene Name keratin 85
Synonyms ECTD4; Hb-5; HB5; hHb5; K85; KRTHB5;
Species Homo sapiens
Ensembl Gene ENSG00000135443
Encoded Proteins
keratin 85
keratin 85
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary The protein encoded by this gene is a member of the keratin gene family. As a type II hair keratin, it is a basic protein which heterodimerizes with type I keratins to form hair and nails. The type II hair keratins are clustered in a region of chromosome 12q13 and are grouped into two distinct subfamilies based on structure similarity. One subfamily, consisting of KRTHB1, KRTHB3, and KRTHB6, is highly related. The other less-related subfamily includes KRTHB2, KRTHB4, and KRTHB5. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 12:52360006-52367481
Strand Reverse strand
Band q13.13
Transcripts
ENST00000257901 ENSP00000257901
ENST00000544265 ENSP00000440240
ENST00000552537
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 21 experimentally validated interaction(s) in this database.
Experimentally validated
Total 21 [view]
Protein-Protein 20 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005198 structural molecule activity
Biological Process
GO:0008544 epidermis development
Cellular Component
GO:0005615 extracellular space
GO:0005882 intermediate filament
GO:0045095 keratin filament
Orthologs
No orthologs found for this gene
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.182507
RefSeq NM_001300810 NM_002283 XM_005268865
HUGO
OMIM
CCDS CCDS73472 CCDS8824
HPRD 04139
IMGT
EMBL
GenPept
RNA Seq Atlas