Version 5.4
Homo sapiens Gene: LARP7
Summary
InnateDB Gene IDBG-34614.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol LARP7
Gene Name La ribonucleoprotein domain family, member 7
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000174720
Encoded Proteins
IDBP-34616
La ribonucleoprotein domain family, member 7
IDBP-34620
La ribonucleoprotein domain family, member 7
IDBP-481840
La ribonucleoprotein domain family, member 7
IDBP-483178
La ribonucleoprotein domain family, member 7
IDBP-478064
La ribonucleoprotein domain family, member 7
IDBP-483430
La ribonucleoprotein domain family, member 7
IDBP-476222
La ribonucleoprotein domain family, member 7
IDBP-480965
La ribonucleoprotein domain family, member 7
IDBP-484388
La ribonucleoprotein domain family, member 7
IDBP-483358
La ribonucleoprotein domain family, member 7
IDBP-482393
La ribonucleoprotein domain family, member 7
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene encodes a protein which is found in the 7SK snRNP (small nuclear ribonucleoprotein). This snRNP complex inhibits a cyclin-dependent kinase, positive transcription elongation factor b, which is required for paused RNA polymerase II at a promoter to begin transcription elongation. A pseudogene of this gene is located on chromosome 3. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2012]
Gene Information
Type Protein coding
Genomic Location Chromosome 4:112636964-112657592
Strand Forward strand
Band q25
Transcripts
ENST00000344442 ENSP00000344950
ENST00000324052 ENSP00000314311
ENST00000512589 ENSP00000426709
ENST00000509061 ENSP00000422626
ENST00000509622 ENSP00000422451
ENST00000508577 ENSP00000426646
ENST00000513553 ENSP00000422013
ENST00000504079
ENST00000505034 ENSP00000421541
ENST00000505216 ENSP00000424116
ENST00000507443 ENSP00000421963
ENST00000503316
ENST00000511529 ENSP00000426376
ENST00000512361
ENST00000503898
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 45 experimentally validated interaction(s) in this database.
Experimentally validated
Total 45 [view]
Protein-Protein 44 [view]
Protein-DNA 0
Protein-RNA 1 [view]
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0000166 nucleotide binding
GO:0003676 nucleic acid binding
GO:0003723 RNA binding
GO:0005515 protein binding
GO:0044822 poly(A) RNA binding
Biological Process
GO:0006396 RNA processing
Cellular Component
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005737 cytoplasm
GO:0005794 Golgi apparatus
GO:0030529 ribonucleoprotein complex
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000027968
View Gene Order
ENSBTAG00000009632
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.713663
RefSeq NM_001267039 NM_015454 NM_016648
HUGO
OMIM
CCDS CCDS3701 CCDS58924
HPRD 17095
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca