Version 5.4
Homo sapiens Gene: CPNE6
Summary
InnateDB Gene IDBG-3473.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol CPNE6
Gene Name copine VI (neuronal)
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000100884
Encoded Proteins
IDBP-236261
copine VI (neuronal)
IDBP-590018
copine VI (neuronal)
IDBP-602877
copine VI (neuronal)
IDBP-602854
copine VI (neuronal)
IDBP-590167
copine VI (neuronal)
IDBP-591997
copine VI (neuronal)
IDBP-592196
copine VI (neuronal)
IDBP-594829
copine VI (neuronal)
IDBP-584989
copine VI (neuronal)
IDBP-595814
copine VI (neuronal)
IDBP-588206
copine VI (neuronal)
IDBP-587975
copine VI (neuronal)
IDBP-596430
copine VI (neuronal)
IDBP-587696
copine VI (neuronal)
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene encodes a brain-specific member of the copine family, which is composed of calcium-dependent membrane-binding proteins. The gene product contains two N-terminal C2 domains, and one von Willebrand factor A domain. It may have a role in synaptic plasticity. [provided by RefSeq, Jul 2008]
This gene encodes a member of the copine family. Members of this family are calcium-dependent, phospholipid-binding proteins with C2 domains, two calcium- and phospholipid-binding domains. Through their domain structure and lipid binding capabilities, these proteins may play a role in membrane trafficking. This protein is thought to be brain-specific and has a domain structure of two N-terminal C2 domains and one von Willebrand factor A domain. It may have a role in synaptic plasticity. [provided by RefSeq, Jul 2013]
Gene Information
Type Protein coding
Genomic Location Chromosome 14:24070837-24078100
Strand Forward strand
Band q11.2
Transcripts
ENST00000397016 ENSP00000380211
ENST00000460657
ENST00000560356 ENSP00000454192
ENST00000558450 ENSP00000454093
ENST00000558995
ENST00000559778 ENSP00000453483
ENST00000560761 ENSP00000454075
ENST00000557889 ENSP00000454166
ENST00000558541 ENSP00000453352
ENST00000558859 ENSP00000453326
ENST00000560092
ENST00000559197 ENSP00000452826
ENST00000560828 ENSP00000453261
ENST00000560884 ENSP00000452884
ENST00000558795 ENSP00000454172
ENST00000559207 ENSP00000452653
ENST00000557829
ENST00000560845
ENST00000537691 ENSP00000440077
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 20 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 20 [view]
Protein-Protein 19 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0001786 phosphatidylserine binding
GO:0005215 transporter activity
GO:0005509 calcium ion binding
GO:0005515 protein binding
Biological Process
GO:0006629 lipid metabolic process
GO:0007268 synaptic transmission
GO:0007399 nervous system development
GO:0016192 vesicle-mediated transport
Cellular Component
GO:0016020 membrane
GO:0030424 axon
GO:0030425 dendrite
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000022212
View Gene Order
ENSBTAG00000001870
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.6132 Hs.732294
RefSeq NM_001280558 NM_006032 XM_005268216 XM_005268217
HUGO
OMIM
CCDS CCDS61413 CCDS9607
HPRD 05748
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca