Version 5.4
Homo sapiens Gene: KRT77
Summary
InnateDB Gene IDBG-34921.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol KRT77
Gene Name keratin 77
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000189182
Encoded Proteins
IDBP-34923
keratin 77
IDBP-596121
keratin 77
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into epithelial keratins and hair keratins. This gene encodes an epithelial keratin that is expressed in the skin and eccrine sweat glands. The type II keratins are clustered in a region of chromosome 12q13.[provided by RefSeq, Jun 2009]
Gene Information
Type Protein coding
Genomic Location Chromosome 12:52689626-52703463
Strand Reverse strand
Band q13.13
Transcripts
ENST00000341809 ENSP00000342710
ENST00000553168 ENSP00000448207
ENST00000550823
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 12 experimentally validated interaction(s) in this database.
They are also associated with 7 interaction(s) predicted by orthology.
Experimentally validated
Total 12 [view]
Protein-Protein 12 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 7 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
GO:0005198 structural molecule activity
Biological Process
GO:0008150 biological_process
Cellular Component
GO:0005856 cytoskeleton
GO:0005882 intermediate filament
GO:0045095 keratin filament
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000067594
View Gene Order
ENSBTAG00000045770
Not yet available
Cross-References
SwissProt
TrEMBL F8VS61
UniProt Splice Variant
Entrez Gene 374454
UniGene Hs.334989
RefSeq NM_175078
HUGO HGNC:20411
OMIM 611158
CCDS CCDS8837
HPRD 13934
IMGT
EMBL AC055716
GenPept
RNA Seq Atlas 374454

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca