Homo sapiens Gene: DCAF11
Summary
InnateDB Gene IDBG-3500.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol DCAF11
Gene Name DDB1 and CUL4 associated factor 11
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000100897
Encoded Proteins
DDB1 and CUL4 associated factor 11
DDB1 and CUL4 associated factor 11
DDB1 and CUL4 associated factor 11
DDB1 and CUL4 associated factor 11
DDB1 and CUL4 associated factor 11
DDB1 and CUL4 associated factor 11
DDB1 and CUL4 associated factor 11
DDB1 and CUL4 associated factor 11
DDB1 and CUL4 associated factor 11
DDB1 and CUL4 associated factor 11
DDB1 and CUL4 associated factor 11
DDB1 and CUL4 associated factor 11
DDB1 and CUL4 associated factor 11
DDB1 and CUL4 associated factor 11
DDB1 and CUL4 associated factor 11
DDB1 and CUL4 associated factor 11
DDB1 and CUL4 associated factor 11
DDB1 and CUL4 associated factor 11
DDB1 and CUL4 associated factor 11
DDB1 and CUL4 associated factor 11
DDB1 and CUL4 associated factor 11
DDB1 and CUL4 associated factor 11
DDB1 and CUL4 associated factor 11
DDB1 and CUL4 associated factor 11
DDB1 and CUL4 associated factor 11
DDB1 and CUL4 associated factor 11
DDB1 and CUL4 associated factor 11
DDB1 and CUL4 associated factor 11
DDB1 and CUL4 associated factor 11
DDB1 and CUL4 associated factor 11
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene encodes a WD repeat-containing protein that interacts with the COP9 signalosome, a macromolecular complex that interacts with cullin-RING E3 ligases and regulates their activity by hydrolyzing cullin-Nedd8 conjugates. Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jul 2009]
Gene Information
Type Protein coding
Genomic Location Chromosome 14:24114195-24125242
Strand Forward strand
Band q12
Transcripts
ENST00000326009 ENSP00000323680
ENST00000396941 ENSP00000380146
ENST00000396936 ENSP00000380142
ENST00000446197 ENSP00000415556
ENST00000559017 ENSP00000453470
ENST00000561056
ENST00000559115 ENSP00000452898
ENST00000558215 ENSP00000454044
ENST00000557809
ENST00000557810 ENSP00000453074
ENST00000561375 ENSP00000453916
ENST00000557802 ENSP00000453462
ENST00000559796 ENSP00000453381
ENST00000560713 ENSP00000453208
ENST00000560901 ENSP00000453132
ENST00000559382 ENSP00000453587
ENST00000561001 ENSP00000453678
ENST00000559396 ENSP00000453290
ENST00000560457 ENSP00000453814
ENST00000558706 ENSP00000453803
ENST00000561016
ENST00000560171
ENST00000560614 ENSP00000453632
ENST00000558638 ENSP00000453505
ENST00000561041 ENSP00000454129
ENST00000559288 ENSP00000454139
ENST00000557952
ENST00000558408 ENSP00000453805
ENST00000557888 ENSP00000453550
ENST00000559354 ENSP00000453832
ENST00000560459 ENSP00000453826
ENST00000559593 ENSP00000452915
ENST00000558914 ENSP00000453035
ENST00000559451 ENSP00000453184
ENST00000560046
ENST00000558624
ENST00000559144 ENSP00000453115
ENST00000559472
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 25 experimentally validated interaction(s) in this database.
Experimentally validated
Total 25 [view]
Protein-Protein 24 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
GO:0016567 protein ubiquitination
Cellular Component
GO:0080008 Cul4-RING E3 ubiquitin ligase complex
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
Method
Confidence
Comments
SSD Ortholog
Ortholog supports species divergence
Not yet available
SSD Ortholog
Ortholog supports species divergence
Cross-References
SwissProt
TrEMBL H0YLQ1 H0YN21
UniProt Splice Variant
Entrez Gene 80344
UniGene Hs.525251 Hs.604632
RefSeq NM_001163484 NM_025230 NM_181357
HUGO HGNC:20258
OMIM 613317
CCDS CCDS9610 CCDS41929
HPRD 18297
IMGT
EMBL AL136295
GenPept
RNA Seq Atlas 80344