Version 5.4
Homo sapiens Gene: COG5
Summary
InnateDB Gene IDBG-35466.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol COG5
Gene Name component of oligomeric golgi complex 5
Synonyms CDG2I; GOLTC1; GTC90
Species Homo sapiens
Ensembl Gene ENSG00000164597
Encoded Proteins
IDBP-35468
component of oligomeric golgi complex 5
IDBP-35470
component of oligomeric golgi complex 5
IDBP-243283
component of oligomeric golgi complex 5
IDBP-808433
component of oligomeric golgi complex 5
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary The protein encoded by this gene is one of eight proteins (Cog1-8) which form a Golgi-localized complex (COG) required for normal Golgi morphology and function. The encoded protein is organized with conserved oligomeric Golgi complex components 6, 7 and 8 into a sub-complex referred to as lobe B. Alternative splicing results in multiple transcript variants. Mutations in this gene result in congenital disorder of glycosylation type 2I.[provided by RefSeq, Jan 2011]
Gene Information
Type Protein coding
Genomic Location Chromosome 7:107201555-107564514
Strand Reverse strand
Band q22.3
Transcripts
ENST00000297135 ENSP00000297135
ENST00000347053 ENSP00000334703
ENST00000393603 ENSP00000377228
ENST00000464542
ENST00000468350
ENST00000462342
ENST00000484237
ENST00000475638
ENST00000469503
ENST00000605888 ENSP00000476238
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 24 experimentally validated interaction(s) in this database.
Experimentally validated
Total 24 [view]
Protein-Protein 21 [view]
Protein-DNA 2 [view]
Protein-RNA 0
DNA-DNA 1 [view]
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
GO:0005515 protein binding
Biological Process
GO:0006891 intra-Golgi vesicle-mediated transport
GO:0015031 protein transport
Cellular Component
GO:0000139 Golgi membrane
GO:0005794 Golgi apparatus
GO:0005829 cytosol
GO:0016020 membrane
GO:0017119 Golgi transport complex
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000035933
View Gene Order
ENSBTAG00000005526
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.239631
RefSeq NM_001161520 NM_006348 NM_181733
HUGO
OMIM
CCDS CCDS55152 CCDS5742 CCDS5743
HPRD 08436
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca