Homo sapiens Gene: EPT1
Summary
InnateDB Gene IDBG-35563.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol EPT1
Gene Name ethanolaminephosphotransferase 1 (CDP-ethanolamine-specific)
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000138018
Encoded Proteins
ethanolaminephosphotransferase 1 (CDP-ethanolamine-specific)
ethanolaminephosphotransferase 1 (CDP-ethanolamine-specific)
ethanolaminephosphotransferase 1 (CDP-ethanolamine-specific)
ethanolaminephosphotransferase 1 (CDP-ethanolamine-specific)
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene encodes a selenoprotein, which contains a selenocysteine (Sec) residue at its active site. The selenocysteine is encoded by the UGA codon that normally signals translation termination. The 3' UTR of selenoprotein genes have a common stem-loop structure, the sec insertion sequence (SECIS), that is necessary for the recognition of UGA as a Sec codon rather than as a stop signal. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 2:26308547-26395891
Strand Forward strand
Band p23.3
Transcripts
ENST00000260585 ENSP00000260585
ENST00000442141 ENSP00000415280
ENST00000447170 ENSP00000391804
ENST00000462301
ENST00000613142 ENSP00000479973
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.
Experimentally validated
Total 3 [view]
Protein-Protein 3 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0004307 ethanolaminephosphotransferase activity
GO:0016780 phosphotransferase activity, for other substituted phosphate groups
GO:0046872 metal ion binding
Biological Process
GO:0006644 phospholipid metabolic process
GO:0006646 phosphatidylethanolamine biosynthetic process
GO:0008654 phospholipid biosynthetic process
GO:0044281 small molecule metabolic process
GO:0046474 glycerophospholipid biosynthetic process
Cellular Component
GO:0005789 endoplasmic reticulum membrane
GO:0016020 membrane
GO:0016021 integral component of membrane
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
Method
Confidence
Comments
SSD Ortholog
Ortholog supports species divergence
Not yet available
SSD Ortholog
Ortholog supports species divergence
Pathways
NETPATH
REACTOME
Metabolism of lipids and lipoproteins pathway
Glycerophospholipid biosynthesis pathway
Phospholipid metabolism pathway
Synthesis of PE pathway
Metabolism pathway
KEGG
Glycerophospholipid metabolism pathway
Ether lipid metabolism pathway
INOH
PID BIOCARTA
PID NCI
Cross-References
SwissProt
TrEMBL C9JAG1
UniProt Splice Variant
Entrez Gene 85465
UniGene Hs.189073
RefSeq NM_033505
HUGO HGNC:29361
OMIM 607915
CCDS CCDS46240
HPRD 07616
IMGT
EMBL AC010896
GenPept
RNA Seq Atlas 85465