Homo sapiens Gene: HAUS8
Summary
InnateDB Gene IDBG-35983.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol HAUS8
Gene Name HAUS augmin-like complex, subunit 8
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000131351
Encoded Proteins
HAUS augmin-like complex, subunit 8
HAUS augmin-like complex, subunit 8
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary HAUS8 is 1 of 8 subunits of the 390-kD human augmin complex, or HAUS complex. The augmin complex was first identified in Drosophila, and its name comes from the Latin verb 'augmentare,' meaning 'to increase.' The augmin complex is a microtubule-binding complex involved in microtubule generation within the mitotic spindle and is vital to mitotic spindle assembly (Goshima et al., 2008 [PubMed 18443220]; Uehara et al., 2009 [PubMed 19369198]).[supplied by OMIM, Jun 2010]
Gene Information
Type Protein coding
Genomic Location Chromosome 19:17049729-17075625
Strand Reverse strand
Band p13.11
Transcripts
ENST00000253669 ENSP00000253669
ENST00000448593 ENSP00000395298
ENST00000593360 ENSP00000470829
ENST00000601564 ENSP00000473111
ENST00000597479
ENST00000595958
ENST00000598517 ENSP00000471868
ENST00000597917
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 15 experimentally validated interaction(s) in this database.
Experimentally validated
Total 15 [view]
Protein-Protein 15 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
Biological Process
GO:0007067 mitotic nuclear division
GO:0051225 spindle assembly
GO:0051297 centrosome organization
Cellular Component
GO:0000922 spindle pole
GO:0005737 cytoplasm
GO:0005813 centrosome
GO:0005874 microtubule
GO:0070652 HAUS complex
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.404088
RefSeq NM_001011699 NM_033417
HUGO
OMIM
CCDS CCDS32948 CCDS46009
HPRD 11318
IMGT
EMBL
GenPept
RNA Seq Atlas