InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Gene: NLK

Summary

InnateDB Gene

IDBG-36215.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

NLK

Gene Name

nemo-like kinase

Synonyms

Species

Homo sapiens

Ensembl Gene

ENSG00000087095

Encoded Proteins

IDBP-293379

nemo-like kinase

IDBP-599884

nemo-like kinase

IDBP-764124

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.

Gene Information

Type

Protein coding

Genomic Location

Chromosome 17:28041737-28196381

Strand

Forward strand

Band

q11.2

Transcripts

ENST00000407008	ENSP00000384625
ENST00000496808	ENSP00000433117
ENST00000584188
ENST00000584878
ENST00000583517
ENST00000582037	ENSP00000464656

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 73 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.

Experimentally validated
Total	73 [view]
Protein-Protein	71 [view]
Protein-DNA	1 [view]
Protein-RNA	0
DNA-DNA	1 [view]
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	2 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0000287	magnesium ion binding
GO:0004672	protein kinase activity
GO:0004674	protein serine/threonine kinase activity
GO:0004707	MAP kinase activity
GO:0004713	protein tyrosine kinase activity
GO:0005515	protein binding
GO:0005524	ATP binding
GO:0008134	transcription factor binding
GO:0016772	transferase activity, transferring phosphorus-containing groups
GO:0031625	ubiquitin protein ligase binding
GO:0042169	SH2 domain binding

Biological Process

GO:0006351	transcription, DNA-templated
GO:0006355	regulation of transcription, DNA-templated
GO:0006468	protein phosphorylation
GO:0007179	transforming growth factor beta receptor signaling pathway
GO:0016055	Wnt signaling pathway
GO:0018107	peptidyl-threonine phosphorylation
GO:0030178	negative regulation of Wnt signaling pathway
GO:0033136	serine phosphorylation of STAT3 protein
GO:0035556	intracellular signal transduction
GO:0046777	protein autophosphorylation