Homo sapiens Gene: SLC5A6
Summary
InnateDB Gene IDBG-37411.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol SLC5A6
Gene Name solute carrier family 5 (sodium-dependent vitamin transporter), member 6
Synonyms SMVT;
Species Homo sapiens
Ensembl Gene ENSG00000138074
Encoded Proteins
solute carrier family 5 (sodium-dependent vitamin transporter), member 6
solute carrier family 5 (sodium-dependent vitamin transporter), member 6
solute carrier family 5 (sodium-dependent vitamin transporter), member 6
solute carrier family 5 (sodium-dependent vitamin transporter), member 6
solute carrier family 5 (sodium-dependent vitamin transporter), member 6
solute carrier family 5 (sodium-dependent vitamin transporter), member 6
solute carrier family 5 (sodium-dependent vitamin transporter), member 6
solute carrier family 5 (sodium-dependent vitamin transporter), member 6
solute carrier family 5 (sodium-dependent vitamin transporter), member 6
solute carrier family 5 (sodium-dependent vitamin transporter), member 6
solute carrier family 5 (sodium-dependent vitamin transporter), member 6
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 2:27199587-27212958
Strand Reverse strand
Band p23.3
Transcripts
ENST00000310574 ENSP00000310208
ENST00000408041 ENSP00000384853
ENST00000401463 ENSP00000384265
ENST00000445802 ENSP00000411361
ENST00000412471 ENSP00000403851
ENST00000432106 ENSP00000411536
ENST00000426119 ENSP00000401347
ENST00000414408 ENSP00000404032
ENST00000428518 ENSP00000402903
ENST00000430186 ENSP00000399299
ENST00000442731 ENSP00000412115
ENST00000461757
ENST00000488743
ENST00000461319
ENST00000481751
ENST00000492069
ENST00000476319
ENST00000464538
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 5 experimentally validated interaction(s) in this database.
Experimentally validated
Total 5 [view]
Protein-Protein 3 [view]
Protein-DNA 2 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005215 transporter activity
GO:0008523 sodium-dependent multivitamin transmembrane transporter activity
Biological Process
GO:0006766 vitamin metabolic process
GO:0006767 water-soluble vitamin metabolic process
GO:0006768 biotin metabolic process
GO:0006810 transport
GO:0006814 sodium ion transport
GO:0015878 biotin transport
GO:0015887 pantothenate transmembrane transport
GO:0015939 pantothenate metabolic process
GO:0044281 small molecule metabolic process
GO:0055085 transmembrane transport
Cellular Component
GO:0005886 plasma membrane
GO:0005887 integral component of plasma membrane
GO:0012506 vesicle membrane
GO:0016020 membrane
GO:0016021 integral component of membrane
GO:0031526 brush border membrane
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
Method
Confidence
Comments
SSD Ortholog
Ortholog supports species divergence
Not yet available
SSD Ortholog
Ortholog supports species divergence
Pathways
NETPATH
REACTOME
Transmembrane transport of small molecules pathway
Defective HLCS causes multiple carboxylase deficiency pathway
Defective MUT causes methylmalonic aciduria mut type pathway
Defective MMAA causes methylmalonic aciduria type cblA pathway
Transport of vitamins, nucleosides, and related molecules pathway
Defective TCN2 causes hereditary megaloblastic anemia pathway
Metabolism of water-soluble vitamins and cofactors pathway
Defective AMN causes hereditary megaloblastic anemia 1 pathway
Defective MTR causes methylmalonic aciduria and homocystinuria type cblG pathway
Defective LMBRD1 causes methylmalonic aciduria and homocystinuria type cblF pathway
Defective CD320 causes methylmalonic aciduria pathway
Defects in cobalamin (B12) metabolism pathway
Defective MMACHC causes methylmalonic aciduria and homocystinuria type cblC pathway
Defects in biotin (Btn) metabolism pathway
Defective BTD causes biotidinase deficiency pathway
Defective GIF causes intrinsic factor deficiency pathway
Vitamin B5 (pantothenate) metabolism pathway
Defects in vitamin and cofactor metabolism pathway
Defective CUBN causes hereditary megaloblastic anemia 1 pathway
Defective MMADHC causes methylmalonic aciduria and homocystinuria type cblD pathway
Defective MTRR causes methylmalonic aciduria and homocystinuria type cblE pathway
Metabolism pathway
Defective MMAB causes methylmalonic aciduria type cblB pathway
SLC-mediated transmembrane transport pathway
Biotin transport and metabolism pathway
Disease pathway
Metabolism of vitamins and cofactors pathway
KEGG
INOH
PID BIOCARTA
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.435735
RefSeq NM_021095 XM_006712128 XM_006712129 XM_006712130
HUGO
OMIM
CCDS CCDS1740
HPRD 04934
IMGT
EMBL
GenPept
RNA Seq Atlas