Version 5.4
Homo sapiens Gene: ARC
Summary
InnateDB Gene IDBG-37634.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol ARC
Gene Name activity-regulated cytoskeleton-associated protein
Synonyms Arg3.1
Species Homo sapiens
Ensembl Gene ENSG00000198576
Encoded Proteins
IDBP-37636
activity-regulated cytoskeleton-associated protein
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 8:142611044-142614472
Strand Reverse strand
Band q24.3
Transcripts
ENST00000356613 ENSP00000349022
ENST00000581404
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 4 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.
Experimentally validated
Total 4 [view]
Protein-Protein 4 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 3 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
GO:0006897 endocytosis
GO:0007010 cytoskeleton organization
GO:0007492 endoderm development
GO:0007612 learning
GO:0009952 anterior/posterior pattern specification
GO:0016477 cell migration
GO:0022604 regulation of cell morphogenesis
GO:0048168 regulation of neuronal synaptic plasticity
Cellular Component
GO:0001669 acrosomal vesicle
GO:0005737 cytoplasm
GO:0005768 endosome
GO:0005886 plasma membrane
GO:0014069 postsynaptic density
GO:0015629 actin cytoskeleton
GO:0030054 cell junction
GO:0043197 dendritic spine
GO:0045211 postsynaptic membrane
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000022602
View Gene Order
ENSBTAG00000021639
Not yet available
Cross-References
SwissProt Q7LC44
TrEMBL
UniProt Splice Variant
Entrez Gene 23237
UniGene Hs.40888
RefSeq NM_015193
HUGO HGNC:648
OMIM 612461
CCDS CCDS34950
HPRD
IMGT
EMBL AF193421 AF248637 BC012321 BC075802 D87468
GenPept AAF07185 AAG33705 AAH12321 AAH75802 BAA19667
RNA Seq Atlas 23237

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca