Version 5.4
Homo sapiens Gene: TSPAN12
Summary
InnateDB Gene IDBG-38100.5
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol TSPAN12
Gene Name tetraspanin 12
Synonyms EVR5; NET-2; NET2; TM4SF12
Species Homo sapiens
Ensembl Gene ENSG00000106025
Encoded Proteins
IDBP-38102
tetraspanin 12
IDBP-385785
tetraspanin 12
IDBP-385786
tetraspanin 12
IDBP-385787
tetraspanin 12
IDBP-385788
tetraspanin 12
IDBP-385790
tetraspanin 12
IDBP-385793
tetraspanin 12
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 7:120787320-120858402
Strand Reverse strand
Band q31.31
Transcripts
ENST00000222747 ENSP00000222747
ENST00000450414 ENSP00000397411
ENST00000415871 ENSP00000397699
ENST00000441017 ENSP00000411158
ENST00000433758 ENSP00000399059
ENST00000424710 ENSP00000404942
ENST00000430985 ENSP00000388819
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
Experimentally validated
Total 2 [view]
Protein-Protein 0
Protein-DNA 2 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
Biological Process
GO:0001525 angiogenesis
GO:0007166 cell surface receptor signaling pathway
GO:0010842 retina layer formation
GO:0045765 regulation of angiogenesis
Cellular Component
GO:0005887 integral component of plasma membrane
GO:0016020 membrane
GO:0016021 integral component of membrane
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000029669
View Gene Order
ENSBTAG00000015337
Not yet available
Cross-References
SwissProt
TrEMBL C9JQM0
UniProt Splice Variant
Entrez Gene 23554
UniGene Hs.16529 Hs.733342
RefSeq NM_012338 XM_005250239
HUGO HGNC:21641
OMIM 613138
CCDS CCDS5777
HPRD 15509
IMGT
EMBL AC004456
GenPept
RNA Seq Atlas 23554

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca