Homo sapiens Gene: TSPAN12
Summary
InnateDB Gene IDBG-38100.5
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol TSPAN12
Gene Name tetraspanin 12
Synonyms EVR5; NET-2; NET2; TM4SF12;
Species Homo sapiens
Ensembl Gene ENSG00000106025
Encoded Proteins
tetraspanin 12
tetraspanin 12
tetraspanin 12
tetraspanin 12
tetraspanin 12
tetraspanin 12
tetraspanin 12
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 7:120787320-120858402
Strand Reverse strand
Band q31.31
Transcripts
ENST00000222747 ENSP00000222747
ENST00000450414 ENSP00000397411
ENST00000415871 ENSP00000397699
ENST00000441017 ENSP00000411158
ENST00000433758 ENSP00000399059
ENST00000424710 ENSP00000404942
ENST00000430985 ENSP00000388819
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
Experimentally validated
Total 2 [view]
Protein-Protein 0
Protein-DNA 2 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
Biological Process
GO:0001525 angiogenesis
GO:0007166 cell surface receptor signaling pathway
GO:0010842 retina layer formation
GO:0045765 regulation of angiogenesis
Cellular Component
GO:0005887 integral component of plasma membrane
GO:0016020 membrane
GO:0016021 integral component of membrane
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
Method
Confidence
Comments
SSD Ortholog
Ortholog supports species divergence
Not yet available
SSD Ortholog
Ortholog supports species divergence
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.16529 Hs.733342
RefSeq NM_012338 XM_005250239
HUGO
OMIM
CCDS CCDS5777
HPRD 15509
IMGT
EMBL
GenPept
RNA Seq Atlas